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KŘIVANOVÁ, Andrea, Roman HÁJEK, Marta KREJČÍ, Vlastimil ŠČUDLA, Karel INDRÁK, J. BAČOVSKÝ, Tomáš BÜCHLER, A. SVOBODNÍK, Zdeněk ADAM, Jiří MAYER and Jiří VORLÍČEK. Second autologous transplantation for multiple myeloma patients relapsing after the first autograft -- a pilot study for the evaluation of experimental maintenance therapies. Report of the prospective non-randomized pilot study of the Czech Myeloma Group. Onkologie. Switzerland: Karger, 2004, vol. 27, No 3, p. 275-279. ISSN 0378-584X.
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Basic information
Original name Second autologous transplantation for multiple myeloma patients relapsing after the first autograft -- a pilot study for the evaluation of experimental maintenance therapies. Report of the prospective non-randomized pilot study of the Czech Myeloma Group
Name in Czech Druhá autologní transplantace u pacientů s MM relabovaných po prvním autoštěpu - pilotní studie pro zhodnocení experimentální udržovací léčby
Authors KŘIVANOVÁ, Andrea (203 Czech Republic), Roman HÁJEK (203 Czech Republic, guarantor), Marta KREJČÍ (203 Czech Republic), Vlastimil ŠČUDLA (203 Czech Republic), Karel INDRÁK (203 Czech Republic), J. BAČOVSKÝ (203 Czech Republic), Tomáš BÜCHLER (703 Slovakia), A. SVOBODNÍK (203 Czech Republic), Zdeněk ADAM (203 Czech Republic), Jiří MAYER (203 Czech Republic) and Jiří VORLÍČEK (203 Czech Republic).
Edition Onkologie, Switzerland, Karger, 2004, 0378-584X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.283
Organization unit Faculty of Medicine
UT WoS 000222477400007
Keywords (in Czech) mnohočetný myelom; autologní transplantace
Keywords in English multiple myeloma; autologous transplantation
Tags autologous transplantation, multiple myeloma
Changed by Changed by: Mgr. Anna Potáčová, Ph.D., učo 44190. Changed: 23/6/2009 13:53.
Abstract
High-dose chemotherapy followed by autologous stem cell transplantation (AT) is accepted as first-line therapy for patients with multiple myeloma (MM), with very good tolerance and low mortality (2-3%). We tested repeated transplantation with different experimental maintenance therapies in patients with MM relapsing/progressing after first AT. Results were compared using intra-individual analyses, therefore inter-individual differences are excluded (T2 model). Repeated AT is a feasible and successful strategy in treatment of relapsing MM; response to second AT and toxicity were acceptable and similar to the first AT in our assessment.
Abstract (in Czech)
V článku je popsán výsledek studie, při níž byla testována druhá autologní transplantace u pacientů s MM.
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