J 2008

Low-dose thalidomide regimens in therapy of relapsed or refractory multiple myeloma

ZEMANOVÁ, M., Vlastimil ŠČUDLA, Zdeněk ADAM, E. GREGORA, Luděk POUR et. al.

Basic information

Original name

Low-dose thalidomide regimens in therapy of relapsed or refractory multiple myeloma

Name in Czech

Režim nízkodávkovaného thalidomidu u léčby relabovaného nebo refrakterního mnohočetného myelomu

Authors

ZEMANOVÁ, M. (203 Czech Republic), Vlastimil ŠČUDLA (203 Czech Republic), Zdeněk ADAM (203 Czech Republic, guarantor), E. GREGORA (203 Czech Republic), Luděk POUR (203 Czech Republic), J. MINAŘÍK (203 Czech Republic), P. PAVLÍČEK (203 Czech Republic), T. PIKA (203 Czech Republic) and Jaroslav BAČOVSKÝ (203 Czech Republic)

Edition

Neoplasma, Bratislava, Slovak Academic Press, Ltd. 2008, 0028-2685

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Slovakia

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.179

RIV identification code

RIV/00216224:14110/08:00035959

Organization unit

Faculty of Medicine

UT WoS

000257128400012

Keywords (in Czech)

mnohočetný myelom; thalidomid

Keywords in English

multiple myeloma; resistance to therapy; thalidomide; cyclophosphamide; dexamethasone

Tags

International impact, Reviewed
Změněno: 24/6/2009 11:15, Mgr. Anna Potáčová, Ph.D.

Abstract

V originále

Thalidomide has been estimated as a useful drug in therapy of refractory or relapsed multiple myeloma. Recently, several studies have shown very good results in therapy combination of thalidomide, cyclophosphamide and dexamethasone, but still high doses of thalidomide associated with serious adverse events have been used. In our study, we performed low-dose thalidomide regimens; the aim of this study was to verify the effect and to assess their toxicity.

In Czech

V této studii jsou popsány režimy léčby v kombinaci s thalidomidem a zhodnocení jejich toxicity.