HOTSPOT WIZARD 1.0

PAVELKA, Antonín, Eva CHOVANCOVÁ and Jiří DAMBORSKÝ. HOTSPOT WIZARD 1.0. 2008.

Basic information

• Original name: HOTSPOT WIZARD 1.0
• Name in Czech: HOTSPOT WIZARD 1.0
• Authors: PAVELKA, Antonín (203 Czech Republic), Eva CHOVANCOVÁ (203 Czech Republic) and Jiří DAMBORSKÝ (203 Czech Republic, guarantor).
• Edition: 2008.

Other information

• Original language: English
• Type of outcome: Software
• Field of Study: 10600 1.6 Biological sciences
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• WWW: Počítačový program pro racionální design mutací
• RIV identification code: RIV/00216224:14310/08:00024502
• Organization unit: Faculty of Science
• Keywords (in Czech): počítačový design mutace
• Keywords in English: computer design mutations hot spots
• Technical parameters: počítačový program

Abstract

HotSpot Wizard is a tool for automatic identification of hot spot sites for engineering of substrate specificity, activity or enantioselectivity of enzymes. HotSpot Wizard integrates several bioinformatics databases and computational tools and represents an easy way to perform several structural and evolutionary analyses at once with minimal demands on users, making this server potentially useful for experimentalists with no prior knowledge of computer modelling or rational protein design.

Abstract (in Czech)

HotSpot Wizard je počítačový program pro design mutací.

Links

• GA201/07/0927, research and development project: Name: Vizualizace proteinových struktur

Investor: Czech Science Foundation, Visualization of protein structures

• IAA100040602, research and development project: Name: Nové přístupy v elektrochemické analýze nukleových kyselin a oligonukleotidů zaměřené na ultrasensitivní mikrodetekci DNA a detekci DNA hybridizace.

Investor: Academy of Sciences of the Czech Republic, New approaches in electrochemical analysis of nucleic acids and oligonucleotides aimed at a ultrasensitive microdetection of DNA and DNA hybridization

• LC06010, research and development project: Name: Centrum biokatalýzy a biotransformací

Investor: Ministry of Education, Youth and Sports of the CR, Center of Biocatalysis and Biotransformation

• MSM0021622412, plan (intention): Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)