R 2008

HOTSPOT WIZARD 1.0

PAVELKA, Antonín, Eva CHOVANCOVÁ and Jiří DAMBORSKÝ

Basic information

Original name

HOTSPOT WIZARD 1.0

Name in Czech

HOTSPOT WIZARD 1.0

Authors

PAVELKA, Antonín (203 Czech Republic), Eva CHOVANCOVÁ (203 Czech Republic) and Jiří DAMBORSKÝ (203 Czech Republic, guarantor)

Edition

2008

Other information

Language

English

Type of outcome

Software

Field of Study

10600 1.6 Biological sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14310/08:00024502

Organization unit

Faculty of Science

Keywords (in Czech)

počítačový design mutace

Keywords in English

computer design mutations hot spots

Technical parameters

počítačový program
Změněno: 2/7/2009 11:45, prof. Mgr. Jiří Damborský, Dr.

Abstract

ORIG CZ

V originále

HotSpot Wizard is a tool for automatic identification of hot spot sites for engineering of substrate specificity, activity or enantioselectivity of enzymes. HotSpot Wizard integrates several bioinformatics databases and computational tools and represents an easy way to perform several structural and evolutionary analyses at once with minimal demands on users, making this server potentially useful for experimentalists with no prior knowledge of computer modelling or rational protein design.

In Czech

HotSpot Wizard je počítačový program pro design mutací.

Links

GA201/07/0927, research and development project
Name: Vizualizace proteinových struktur
Investor: Czech Science Foundation, Visualization of protein structures
IAA100040602, research and development project
Name: Nové přístupy v elektrochemické analýze nukleových kyselin a oligonukleotidů zaměřené na ultrasensitivní mikrodetekci DNA a detekci DNA hybridizace.
Investor: Academy of Sciences of the Czech Republic, New approaches in electrochemical analysis of nucleic acids and oligonucleotides aimed at a ultrasensitive microdetection of DNA and DNA hybridization
LC06010, research and development project
Name: Centrum biokatalýzy a biotransformací
Investor: Ministry of Education, Youth and Sports of the CR, Center of Biocatalysis and Biotransformation
MSM0021622412, plan (intention)
Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)