J 2009

Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)

MIKULA, Přemysl, Kamila KRUŽÍKOVÁ, Radka DOBŠÍKOVÁ, Danka HARUŠTIAKOVÁ, Zdeňka SVOBODOVÁ et. al.

Basic information

Original name

Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)

Name in Czech

Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)

Authors

MIKULA, Přemysl (203 Czech Republic), Kamila KRUŽÍKOVÁ (203 Czech Republic), Radka DOBŠÍKOVÁ (203 Czech Republic), Danka HARUŠTIAKOVÁ (703 Slovakia, guarantor) and Zdeňka SVOBODOVÁ (203 Czech Republic)

Edition

Acta Veterinaria Brno, Brno, Univ. of Vet. and Pharmac Sc. 2009, 0001-7213

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10511 Environmental sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.403

RIV identification code

RIV/00216224:14310/09:00036187

Organization unit

Faculty of Science

UT WoS

000267788000019

Keywords (in Czech)

Fish; parabens; preservatives; sex differentiation; vitellogenin; xeno-oestrogens

Keywords in English

Fish; parabens; preservatives; sex differentiation; vitellogenin; xeno-oestrogens

Tags

International impact, Reviewed
Změněno: 23/2/2010 21:17, RNDr. Danka Haruštiaková, Ph.D.

Abstract

V originále

The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish (Danio rerio). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg-1 of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg-1 of 17-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg-1 of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.

In Czech

The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish (Danio rerio). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg-1 of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg-1 of 17-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg-1 of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.

Links

MSM0021622412, plan (intention)
Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)