Aspergillus fumigatus host-interacting proteins - potential therapeutic targets

HOUSER, Josef, Věra DAŇKOVÁ and Michaela WIMMEROVÁ. Aspergillus fumigatus host-interacting proteins - potential therapeutic targets. In The FEBS Journal. 2009. ISSN 1742-464X.

Basic information

Original name

Aspergillus fumigatus host-interacting proteins - potential therapeutic targets

Name in Czech

Proteiny z Aspergillus fumigatus interagující s hostitelem- potenciální terapeutické cíle

Authors

HOUSER, Josef (203 Czech Republic, belonging to the institution), Věra DAŇKOVÁ (203 Czech Republic, belonging to the institution) and Michaela WIMMEROVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

The FEBS Journal, 2009

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Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

10600 1.6 Biological sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.042

RIV identification code

RIV/00216224:14310/09:00029410

Organization unit

Faculty of Science

ISSN

UT WoS

000267069900399

Keywords (in Czech)

Aspergillus; lektin; cukr-proteinová interakce

Keywords in English

Aspergillus; lectin; sugar-protein interaction

Tags

Aspergillus, lectin, sugar-protein interaction

Tags

International impact

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Abstract

V originále

The binding of Aspergillus to the epithelials is one of the crucial steps in infection. Among others, lectins play an important role here. Studying of this proces on molecular level has a potential to discover a new sort of antifungal drugs with possibly better properties than the current one's.

In Czech

Vazba Aspergillus na epitelie je jedním z klíčových kroků infekce. Vedle dalších zde hrají důležitou roli lektiny. Studování tohoto procesu na molekulární úrovni má potenciál pro odhalení nové skupiny antifungálních léčiv s lepšími vlastnostmi, než mají ta současná.

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Links

GA303/09/1168, research and development project	Name: Lektiny z lidských patogenů - struktura, funkce, inženýrství Investor: Czech Science Foundation, Lectins from human pathogens - structure, function, engineering
GD204/08/H054, research and development project	Name: Molekulární mechanismy proliferace a diferenciace buněk Investor: Czech Science Foundation, Molecular mechanisms of the cell proliferation and differentiation
LC06030, research and development project	Name: Biomolekulární centrum Investor: Ministry of Education, Youth and Sports of the CR, Biomolecular centre
MSM0021622413, plan (intention)	Name: Proteiny v metabolismu a při interakci organismů s prostředím Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment