| CARLTON, Jane, R.P. HIRT, J.C. SILVA, A.L. DELCHER, M. SCHATZ, Q. ZHAO, J.R. WORTMAN, S.L. BIDWELL, U.C. ALSMARK, S. BESTEIRO, T. SICHERITZ-PONTEN, C.J. NOEL, J.B. DACKS, P.G. FOSTER, C. SIMILLION, Y. VAN DE PEER, D. MIRANDA-SAAVEDRA, G.J. BARTON, G.D. WESTROP, S. MULLER, D. DESSI, P.L. FIORI, Q. REN, I. PAULSEN, H. ZHANG, F.D. BASTIDA-CORCUERA, A. SIMOES-BARBOSA, M.T. BROWN, R. HAYES, M. MUKHERJEE, C.Y. OKUMURA, R. SCHNEIDER, A.J. SMITH, Štěpánka VAŇÁČOVÁ, M. VILLALVAZO, B.J. HAAS, M. PERTEA, T. FELDBLYUM, T.R. UTTERBACK, Chung-Li SHU, K. OSOEGAWA, P.J. DE JONG, Ivan HRDY, Lenka HORVATHOVA, Zuzana ZUBACOVA, Pavel DOLEZAL, S.B. MALIK, J.Jr. LOGSDON, K. HENZE, A. GUPTA, C.C. WANG, R.L. DUNNE, J.A. UPCROFT, Peter UPCROFT, Owen WHITE, S.L. SALZBERG, P. TANG, Cheng-Hsun CHIU, Ying-Shiung LEE, T.M. EMBLEY, G.H. COOMBS, J.C. MOTTRAM, Jan TACHEZY, C. FRASER-LIGGETT and Patricia J. JOHNSON. Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. Science. 2007, vol. 315, No 5809, p. 207-212. ISSN 0036-8075. |
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@article{840506,
author = {Carlton, Jane and Hirt, R.P. and Silva, J.C. and Delcher, A.L. and Schatz, M. and Zhao, Q. and Wortman, J.R. and Bidwell, S.L. and Alsmark, U.C. and Besteiro, S. and SicheritzandPonten, T. and Noel, C.J. and Dacks, J.B. and Foster, P.G. and Simillion, C. and Van de Peer, Y. and MirandaandSaavedra, D. and Barton, G.J. and Westrop, G.D. and Muller, S. and Dessi, D. and Fiori, P.L. and Ren, Q. and Paulsen, I. and Zhang, H. and BastidaandCorcuera, F.D. and SimoesandBarbosa, A. and Brown, M.T. and Hayes, R. and Mukherjee, M. and Okumura, C.Y. and Schneider, R. and Smith, A.J. and Vaňáčová, Štěpánka and Villalvazo, M. and Haas, B.J. and Pertea, M. and Feldblyum, T. and Utterback, T.R. and Shu, ChungandLi and Osoegawa, K. and de Jong, P.J. and Hrdy, Ivan and Horvathova, Lenka and Zubacova, Zuzana and Dolezal, Pavel and Malik, S.B. and Logsdon, J.Jr. and Henze, K. and Gupta, A. and Wang, C.C. and Dunne, R.L. and Upcroft, J.A. and Upcroft, Peter and White, Owen and Salzberg, S.L. and Tang, P. and Chiu, ChengandHsun and Lee, YingandShiung and Embley, T.M. and Coombs, G.H. and Mottram, J.C. and Tachezy, Jan and FraserandLiggett, C. and Johnson, Patricia J.},
article_number = {5809},
keywords = {Trichomonas; genome; protozoa; transposon elements; hydrogenosome: mitochondria},
language = {eng},
issn = {0036-8075},
journal = {Science},
title = {Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis},
volume = {315},
year = {2007}
}
TY - JOUR
ID - 840506
AU - Carlton, Jane - Hirt, R.P. - Silva, J.C. - Delcher, A.L. - Schatz, M. - Zhao, Q. - Wortman, J.R. - Bidwell, S.L. - Alsmark, U.C. - Besteiro, S. - Sicheritz-Ponten, T. - Noel, C.J. - Dacks, J.B. - Foster, P.G. - Simillion, C. - Van de Peer, Y. - Miranda-Saavedra, D. - Barton, G.J. - Westrop, G.D. - Muller, S. - Dessi, D. - Fiori, P.L. - Ren, Q. - Paulsen, I. - Zhang, H. - Bastida-Corcuera, F.D. - Simoes-Barbosa, A. - Brown, M.T. - Hayes, R. - Mukherjee, M. - Okumura, C.Y. - Schneider, R. - Smith, A.J. - Vaňáčová, Štěpánka - Villalvazo, M. - Haas, B.J. - Pertea, M. - Feldblyum, T. - Utterback, T.R. - Shu, Chung-Li - Osoegawa, K. - de Jong, P.J. - Hrdy, Ivan - Horvathova, Lenka - Zubacova, Zuzana - Dolezal, Pavel - Malik, S.B. - Logsdon, J.Jr. - Henze, K. - Gupta, A. - Wang, C.C. - Dunne, R.L. - Upcroft, J.A. - Upcroft, Peter - White, Owen - Salzberg, S.L. - Tang, P. - Chiu, Cheng-Hsun - Lee, Ying-Shiung - Embley, T.M. - Coombs, G.H. - Mottram, J.C. - Tachezy, Jan - Fraser-Liggett, C. - Johnson, Patricia J.
PY - 2007
TI - Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis
JF - Science
VL - 315
IS - 5809
SP - 207-212
EP - 207-212
SN - 00368075
KW - Trichomonas
KW - genome
KW - protozoa
KW - transposon elements
KW - hydrogenosome: mitochondria
N2 - We describe the genome sequence of the protist Trichomonas vaginalis, a sexually transmitted human pathogen. Repeats and transposable elements comprise about two-thirds of the ~160-megabase genome, reflecting a recent massive expansion of genetic material. This expansion, in conjunction with the shaping of metabolic pathways that likely transpired through lateral gene transfer from bacteria, and amplification of specific gene families implicated in pathogenesis and phagocytosis of host proteins may exemplify adaptations of the parasite during its transition to a urogenital environment. The genome sequence predicts previously unknown functions for the hydrogenosome, which support a common evolutionary origin of this unusual organelle with mitochondria.
ER -
CARLTON, Jane, R.P. HIRT, J.C. SILVA, A.L. DELCHER, M. SCHATZ, Q. ZHAO, J.R. WORTMAN, S.L. BIDWELL, U.C. ALSMARK, S. BESTEIRO, T. SICHERITZ-PONTEN, C.J. NOEL, J.B. DACKS, P.G. FOSTER, C. SIMILLION, Y. VAN DE PEER, D. MIRANDA-SAAVEDRA, G.J. BARTON, G.D. WESTROP, S. MULLER, D. DESSI, P.L. FIORI, Q. REN, I. PAULSEN, H. ZHANG, F.D. BASTIDA-CORCUERA, A. SIMOES-BARBOSA, M.T. BROWN, R. HAYES, M. MUKHERJEE, C.Y. OKUMURA, R. SCHNEIDER, A.J. SMITH, Štěpánka VAŇÁČOVÁ, M. VILLALVAZO, B.J. HAAS, M. PERTEA, T. FELDBLYUM, T.R. UTTERBACK, Chung-Li SHU, K. OSOEGAWA, P.J. DE JONG, Ivan HRDY, Lenka HORVATHOVA, Zuzana ZUBACOVA, Pavel DOLEZAL, S.B. MALIK, J.Jr. LOGSDON, K. HENZE, A. GUPTA, C.C. WANG, R.L. DUNNE, J.A. UPCROFT, Peter UPCROFT, Owen WHITE, S.L. SALZBERG, P. TANG, Cheng-Hsun CHIU, Ying-Shiung LEE, T.M. EMBLEY, G.H. COOMBS, J.C. MOTTRAM, Jan TACHEZY, C. FRASER-LIGGETT and Patricia J. JOHNSON. Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. \textit{Science}. 2007, vol.~315, No~5809, p.~207-212. ISSN~0036-8075.
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