| LAU, A.O.T., D.R. LISTON, Štěpánka VAŇÁČOVÁ a Patricia J. JOHNSON. Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif. Molecular and Biochemical Parasitology. ELSEVIER, roč. 130, č. 2, s. 167-171. ISSN 0166-6851. 2003. |
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@article{840514,
author = {Lau, A.O.T. and Liston, D.R. and Vaňáčová, Štěpánka and Johnson, Patricia J.},
article_number = {2},
keywords = {Trichomonas; initiator binding protein; transcription; protozoa},
language = {eng},
issn = {0166-6851},
journal = {Molecular and Biochemical Parasitology},
title = {Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif},
volume = {130},
year = {2003}
}
TY - JOUR
ID - 840514
AU - Lau, A.O.T. - Liston, D.R. - Vaňáčová, Štěpánka - Johnson, Patricia J.
PY - 2003
TI - Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif
JF - Molecular and Biochemical Parasitology
VL - 130
IS - 2
SP - 167-171
EP - 167-171
PB - ELSEVIER
SN - 01666851
KW - Trichomonas
KW - initiator binding protein
KW - transcription
KW - protozoa
N2 - This study focuses on the detailed characterization of the only transcription factor identified in the human pathogen Trichomonas vaginalis, the IBP39 protein. Here we show the nuclear localization of IBP39. In addition, we map the DNA binding domain. It resides near the N-terminus of the protein, between amino acids 45 and 71. The residues 66-70 (KMKKK) are critical for DNA binding. This is the first DNA binding domain to be mapped in the only transcription factor in this parasite to date.
ER -
LAU, A.O.T., D.R. LISTON, Štěpánka VAŇÁČOVÁ a Patricia J. JOHNSON. Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif. \textit{Molecular and Biochemical Parasitology}. ELSEVIER, roč.~130, č.~2, s.~167-171. ISSN~0166-6851. 2003.
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