LAU, A.O.T., D.R. LISTON, Štěpánka VAŇÁČOVÁ and Patricia J. JOHNSON. Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif. Molecular and Biochemical Parasitology. ELSEVIER, 2003, vol. 130, No 2, p. 167-171. ISSN 0166-6851.
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Basic information
Original name Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif
Name in Czech Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif
Authors LAU, A.O.T. (840 United States of America), D.R. LISTON (840 United States of America), Štěpánka VAŇÁČOVÁ (203 Czech Republic, guarantor) and Patricia J. JOHNSON (840 United States of America).
Edition Molecular and Biochemical Parasitology, ELSEVIER, 2003, 0166-6851.
Other information
Original language English
Type of outcome Article in a journal
Field of Study Genetics and molecular biology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.882
RIV identification code RIV/00216224:14310/03:00036236
Organization unit Faculty of Science
UT WoS 000185273100016
Keywords (in Czech) Trichomonas; initiator binding protein; transcription; protozoa
Keywords in English Trichomonas; initiator binding protein; transcription; protozoa
Tags initiator binding protein, protozoa, Transcription, Trichomonas
Tags International impact, Reviewed
Changed by Changed by: prof. Mgr. Štěpánka Vaňáčová, Ph.D., učo 105562. Changed: 29/3/2010 16:12.
Abstract
This study focuses on the detailed characterization of the only transcription factor identified in the human pathogen Trichomonas vaginalis, the IBP39 protein. Here we show the nuclear localization of IBP39. In addition, we map the DNA binding domain. It resides near the N-terminus of the protein, between amino acids 45 and 71. The residues 66-70 (KMKKK) are critical for DNA binding. This is the first DNA binding domain to be mapped in the only transcription factor in this parasite to date.
Abstract (in Czech)
This study focuses on the detailed characterization of the only transcription factor identified in the human pathogen Trichomonas vaginalis, the IBP39 protein. Here we show the nuclear localization of IBP39. In addition, we map the DNA binding domain. It resides near the N-terminus of the protein, between amino acids 45 and 71. The residues 66-70 (KMKKK) are critical for DNA binding. This is the first DNA binding domain to be mapped in the only transcription factor in this parasite to date.
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