Insulin Decreases Transcription of Three Proteins Associated with Lung Surfactant

RUČKA, Zdeněk, Petr VAŇHARA, Lenka TESAŘOVÁ, Michaela POTĚŠILOVÁ, Stanislav STEJSKAL, Jan DOLEŽEL and Irena KOUTNÁ. Insulin Decreases Transcription of Three Proteins Associated with Lung Surfactant. 2009th ed. [e-mail], 2009. The Online Journal of Scientific Posters.

Basic information

• Original name: Insulin Decreases Transcription of Three Proteins Associated with Lung Surfactant
• Name in Czech: Inzulín snižuje transkripci třech proteinů asociovaných s plicním surfaktantem
• Authors: RUČKA, Zdeněk (203 Czech Republic, belonging to the institution), Petr VAŇHARA (203 Czech Republic, belonging to the institution), Lenka TESAŘOVÁ (203 Czech Republic, belonging to the institution), Michaela POTĚŠILOVÁ (203 Czech Republic, belonging to the institution), Stanislav STEJSKAL (203 Czech Republic, belonging to the institution), Jan DOLEŽEL (203 Czech Republic) and Irena KOUTNÁ (203 Czech Republic, guarantor, belonging to the institution).
• Edition: 2009. vyd. The Online Journal of Scientific Posters, 2009.
• Publisher: [e-mail]

Other information

• Original language: English
• Type of outcome: Audiovisual works
• Field of Study: Genetics and molecular biology
• Country of publisher: Germany
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• RIV identification code: RIV/00216224:14330/09:00036671
• Organization unit: Faculty of Informatics
• Keywords (in Czech): inzulín surfaktant PCR
• Keywords in English: insulin surfactant PCR
• Tags: cbia-web

Abstract

There are four proteins associated with lung surfactant. Low quality or quantity of these proteins often causes severe symptoms in lungs. We demonstrated that insulin serves as a negative regulator of transcription of proteins associated with lungs surfactant in H441 and A549 cell lines.

Abstract (in Czech)

Existují čtyři proteiny asociované s plicním surfaktantem. Nízká kvalita nebo kvantita těchto proteinů v plicích často vyvolává závažné symptomy. Ukázali jsme, že inzulín funguje jako negativní regulátor transkripce proteinů asociovaných s plicním surfaktantem v buněčných liniích H441 a A549.

Links

• NS9681, research and development project: Name: Studium molekulárně-biologické odpovědi na intenzivní inzulínovou terapii při plicních resekcích

Investor: Ministry of Health of the CR

• 2B06052, research and development project: Name: Vytipování markerů, screening a časná diagnostika nádorových onemocnění pomocí vysoce automatizovaného zpracování multidimenzionálních biomedicínských obrazů (Acronym: Biomarker)

Investor: Ministry of Education, Youth and Sports of the CR, Determination of markers, screening and early diagnostics of cancer diseases using highly automated processing of multidimensional biomedical images