J 2008

HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT STUDY FOR SCORING OF THE DIC

LIPOVÝ, Břetislav, Yvona KALOUDOVÁ, Miloslava MATÝŠKOVÁ, Miroslav PENKA, Hana ŘIHOVÁ et. al.

Basic information

Original name

HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT STUDY FOR SCORING OF THE DIC

Name in Czech

Hemokoagulační poruchy u těžce popálených pacientů: pilotní studie ke skórování DIC

Authors

LIPOVÝ, Břetislav (203 Czech Republic, guarantor), Yvona KALOUDOVÁ (203 Czech Republic), Miloslava MATÝŠKOVÁ (203 Czech Republic), Miroslav PENKA (203 Czech Republic), Hana ŘIHOVÁ (203 Czech Republic) and Pavel BRYCHTA (203 Czech Republic)

Edition

Acta chirurgiae plasticae, Praha, 2008, 1803-6597

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/08:00036699

Organization unit

Faculty of Medicine

Keywords in English

DIC haemocoagulation assesment burn trauma D dimers

Tags

Reviewed

Abstract

V originále

Goal of the study. To apply results of the hemocoagulation parameters to the DIC (disseminated intravascular coagulation) score system. Compare parameters of the DIC score in patients with extensive burn trauma (hospitalized at the Intensive Care Unit, ICU) and patients with lesser extent of burn injury (hospitalized at the standard unit). To use these data within the evidence based medicine for the prediction of organ damage and multi organ failure. Type of study. Prospective study. Material and methods. We have included total of 36 patients in the group within four months. Twelve patients were hospitalized at the ICU, 24 patients were hospitalized at the intermedial care and standard unit. Repeatedly, we have taken blood from patients to evaluate the hemocoagulation parameters. In patients hospitalized at the ICU, the blood was taken from the central vein (prior to the drawn, the access was flushed with 100ml of F1/1, the blood was taken from different access than from the one administering heparin), in patients hospitalized at the standard unit the blood was taken from a peripheral vein. The results were then put into the tables established according to the ISTH (International Society on Thrombosis and Hemostasis). Next, the DIC score was calculated to predict severity of hemocoagulation balance disorders in burn trauma, or occurrence of complications during the treatment. Results. Part 1: We have evaluated 12 patients (4 females) hospitalized at the ICU. At the day of injury the overt DIC score reached 1.25 (0 3), fifth day after the injury the average value of overt DIC score was 1.83 (0 3), one day after the autotransplantation it was 2.08 (0 3) and at the day of discharge from the hospital 0. In the deceased patient the DIC score reached value of 2. Part 2: We evaluated 24 patients (10 females) hospitalized at the standard unit. The extent of their burn injury was 5.9% TBSA (0.5 12% TBSA), age 49.13 years (17 94 years). At the day of injury the overt DIC score reached 0.25 (0 2). Fifth day after the injury the average value of overt DIC score was 1.66 (0 2). Day after the autotransplantation it was 1.83 (0 3) and at the day of discharge 0.02 (0 2). Conclusion. During the treatment of the patients with various extent of burn injury, none of the patients scores reached values that would mean occurrence of obvious overt DIC.