Expression pattern of HLA class I antigens in renal cell
carsinoma and primary cell line cultures: Methodological
implications for immunotherapy

J 2009

Expression pattern of HLA class I antigens in renal cell carsinoma and primary cell line cultures: Methodological implications for immunotherapy

HANÁK, Libor, Ondřej SLABÝ, Ludmila LAUEROVÁ, Leoš KŘEN, Rudolf NENUTIL et. al.

Basic information

Original name

Expression pattern of HLA class I antigens in renal cell carsinoma and primary cell line cultures: Methodological implications for immunotherapy

Name in Czech

Expresní profil HLA antigenů I třídy u renálního karcinomu a primárních buněčých linií: metodologický význam v imunoterapii

Authors

HANÁK, Libor (203 Czech Republic), Ondřej SLABÝ (203 Czech Republic), Ludmila LAUEROVÁ (203 Czech Republic), Leoš KŘEN (203 Czech Republic), Rudolf NENUTIL (203 Czech Republic) and Jaroslav MICHÁLEK (203 Czech Republic, guarantor)

Edition

Medical Science Monitor (International Medical Journal of Experimental and Clinical Research), USA, International Scientific Literature, Inc, 2009, 1234-1010

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.543

RIV identification code

RIV/00216224:14110/09:00036993

Organization unit

Faculty of Medicine

UT WoS

000273120300013

Keywords (in Czech)

renální karcinom; imunoterapie; HLA antigeny

Keywords in English

renal carcinoma; immunotherapy; HLA antigens

Změněno: 10/12/2009 13:09, Mgr. Anna Potáčová, Ph.D.

Abstract

ORIG CZ

V originále

In this study both classic and non-classic HLA cals I antigens were tested in tumor specimens and estabilished primary cell cultures derived from renal cell carcinoma patients. Our findings suggest that primary cell line cultures derived from surgical specimens of renal cell carcinomas are a feasible model for immunotherapy research through their high cultivation protential.

In Czech

V této studii byly studovány HLA antigeny na primárních nádorových kulturách získaných od pacientů s renálním karcinomem. Bylo zjištěno, že tyto kultury jsou vhodné pro další imunoterapeutický výzkum, díky jejich vysokému kultvačnímu potenciálu.

Links

2B06058, research and development project

Name: Bezpečná biotechnologie alotransplantovaných hematopoetických kmenových buněk u vybraných solidních a hematologických nádorů jako adoptivní imunoterapie (Acronym: NPVII11001)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

HANÁK, Libor, Ondřej SLABÝ, Ludmila LAUEROVÁ, Leoš KŘEN, Rudolf NENUTIL and Jaroslav MICHÁLEK. Expression pattern of HLA class I antigens in renal cell carsinoma and primary cell line cultures: Methodological implications for immunotherapy. Medical Science Monitor (International Medical Journal of Experimental and Clinical Research). USA: International Scientific Literature, Inc, 2009, vol. 15, No 12, p. CR638-CR643, 6 pp. ISSN 1234-1010.

@article{852116,
   author = {Hanák, Libor and Slabý, Ondřej and Lauerová, Ludmila and Křen, Leoš and Nenutil, Rudolf and Michálek, Jaroslav},
   article_location = {USA},
   article_number = {12},
   keywords = {renal carcinoma; immunotherapy; HLA antigens},
   language = {eng},
   issn = {1234-1010},
   journal = {Medical Science Monitor (International Medical Journal of Experimental and Clinical Research)},
   title = {Expression pattern of HLA class I antigens in renal cell carsinoma and primary cell line cultures: Methodological implications for immunotherapy},
   volume = {15},
   year = {2009}
}

TY  - JOUR
ID  - 852116
AU  - Hanák, Libor - Slabý, Ondřej - Lauerová, Ludmila - Křen, Leoš - Nenutil, Rudolf - Michálek, Jaroslav
PY  - 2009
TI  - Expression pattern of HLA class I antigens in renal cell carsinoma and primary cell line cultures: Methodological implications for immunotherapy
JF  - Medical Science Monitor (International Medical Journal of Experimental and Clinical Research)
VL  - 15
IS  - 12
SP  - CR638-CR643
EP  - CR638-CR643
PB  - International Scientific Literature, Inc
SN  - 12341010
KW  - renal carcinoma
KW  - immunotherapy
KW  - HLA antigens
N2  - In this study both classic and non-classic HLA cals I antigens were tested in tumor specimens and estabilished primary cell cultures derived from renal cell carcinoma patients. Our findings suggest that primary cell line cultures derived from surgical specimens of renal cell carcinomas are a feasible model for immunotherapy research through their high cultivation protential.
ER  -

HANÁK, Libor, Ondřej SLABÝ, Ludmila LAUEROVÁ, Leoš KŘEN, Rudolf NENUTIL and Jaroslav MICHÁLEK. Expression pattern of HLA class I antigens in renal cell carsinoma and primary cell line cultures: Methodological implications for immunotherapy. \textit{Medical Science Monitor (International Medical Journal of Experimental and Clinical Research)}. USA: International Scientific Literature, Inc, 2009, vol.~15, No~12, p.~CR638-CR643, 6 pp. ISSN~1234-1010.

Detailed Information on Publication Record