ŠLAIS, Karel, Leoš LANDA and Alexandra ŠULCOVÁ. MDMA decreases sociability and aggression and increases anxiety in mouse model of agonistic behaviour. Activitas Nervosa Superior Rediviva. 2009, 51/2009, 1-2, p. 79-80. ISSN 1337-933X.
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Basic information
Original name MDMA decreases sociability and aggression and increases anxiety in mouse model of agonistic behaviour
Name in Czech MDMA snižuje sociabilitu a agresivitu a zvyšuje plachost v modelu agonistického chování u myší
Authors ŠLAIS, Karel (203 Czech Republic, guarantor), Leoš LANDA (203 Czech Republic) and Alexandra ŠULCOVÁ (203 Czech Republic).
Edition Activitas Nervosa Superior Rediviva, 2009, 1337-933X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Slovakia
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/09:00037028
Organization unit Faculty of Medicine
Keywords (in Czech) MDMA; agresivita; sociabilita; anxieta; agonistické chování
Keywords in English MDMA; aggressivity; sociability; anxiety; agonistic behaviour
Tags International impact, Reviewed
Changed by Changed by: MUDr. Mgr. Karel Šlais, Ph.D., učo 19989. Changed: 30/10/2009 09:38.
Abstract
We evaluated acute effects of methylen-dioxy-methamphetamine (MDMA) on agonistic behaviour in singly-housed mice on paired conflict interactions with group-housed partners. We fully confirmed the antiaggressive effects and increase of defensive-escape behaviour in aggressive mice. The analysis of timid mice brought evidence of anxiogenic effect of MDMA.
Abstract (in Czech)
Práce studovala akutní účinky methylen-dioxy-methamphetaminu na chování samostatně chovaných myší v párových interakcích s partnery ze skupinového ustájení. Prokázali jsme antiagresivní účinky MDMA a zvýšení plachosti u agresivních myší. Sledování plachých myší potvrdilo anxiogenní účinky MDMA.
Links
MSM0021622404, plan (intention)Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
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