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@inproceedings{854416,
author = {Dubový, Petr and David, Marek and Klusáková, Ilona and Hradilová Svíženská, Ivana},
address = {Bologna (Italy)},
booktitle = {9th European Meeting on Glial Cells in Health and Disease},
edition = {1st},
keywords = {behavioral tests; bilateral reaction of spinal nerve roots; dorsal root; endoneurium; laminin-1; neuropathic pain; peripheral nervous system; unilateral constriction of sciatic nerve; ventral root},
language = {eng},
location = {Bologna (Italy)},
isbn = {978-88-7587-520-6},
pages = {89-92},
publisher = {Medimond S.r.l.},
title = {Bilateral quantitative changes of laminin-1 in the spinal nerve roots after unilateral sciatic nerve injury},
url = {http://www.medimond.com/proceedings/detail.asp?id=20090908C},
year = {2009}
}
TY - JOUR
ID - 854416
AU - Dubový, Petr - David, Marek - Klusáková, Ilona - Hradilová Svíženská, Ivana
PY - 2009
TI - Bilateral quantitative changes of laminin-1 in the spinal nerve roots after unilateral sciatic nerve injury
PB - Medimond S.r.l.
CY - Bologna (Italy)
SN - 9788875875206
KW - behavioral tests
KW - bilateral reaction of spinal nerve roots
KW - dorsal root
KW - endoneurium
KW - laminin-1
KW - neuropathic pain
KW - peripheral nervous system
KW - unilateral constriction of sciatic nerve
KW - ventral root
UR - http://www.medimond.com/proceedings/detail.asp?id=20090908C
N2 - Changes of laminin-1 (lam-1) were investigated in rat spinal nerve roots after unilateral sciatic nerve ligature. Spinal nerve roots of naive rats displayed lam-1 immunostaining in the basal laminae on outer surface of Schwann cell/axon units with higher brightness in ventral than dorsal roots. Bilateral enhancement of lam-1 immunofluorescence was found in the endoneurium of roots 1 and 3 days after nerve ligature. Compared to rats surviving for 1 or 3 days, apparent bilateral decrease of lam-1 immunofluorescence brightness was observed in both roots 7 days after nerve injury. The lam-1 alterations in ipsi- and contralateral roots were similar, but more distinct in roots of ipsilateral side. The results suggest that quantitative changes of lam-1 are present bilaterally in the endoneurium of spinal nerve roots after unilateral sciatic nerve ligature.
ER -
DUBOVÝ, Petr, Marek DAVID, Ilona KLUSÁKOVÁ a Ivana HRADILOVÁ SVÍŽENSKÁ. Bilateral quantitative changes of laminin-1 in the spinal nerve roots after unilateral sciatic nerve injury. In \textit{9th European Meeting on Glial Cells in Health and Disease}. 1st. Bologna (Italy): Medimond S.r.l., 2009, s.~89-92. ISBN~978-88-7587-520-6.
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