Detailed Information on Publication Record
2009
) Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter
MRAVEC, Jozef, Petr SKŮPA, Aurélien BAILLY, Klára HOYEROVÁ, Pavel KŘEČEK et. al.Basic information
Original name
) Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter
Name in Czech
) Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter
Authors
MRAVEC, Jozef (705 Slovenia), Petr SKŮPA (203 Czech Republic), Aurélien BAILLY (756 Switzerland), Klára HOYEROVÁ (203 Czech Republic), Pavel KŘEČEK (203 Czech Republic), Agnieszka BIELACH (616 Poland), Jan PETRÁŠEK (203 Czech Republic), Jing ZHANG (156 China), Vassilena GAYKOVA (100 Bulgaria), York-Dieter STIERHOF (276 Germany), Petre I. DOBREV (804 Ukraine), Kateřina SCHWARZEROVÁ (203 Czech Republic), Jakub ROLČÍK (203 Czech Republic), Daniela SEIFERTOVÁ (203 Czech Republic), Christian LUSCHNIG (40 Austria), Eva BENKOVÁ (703 Slovakia), Eva ZAŽÍMALOVÁ (203 Czech Republic), Markus GEISLER (756 Switzerland) and Jiří FRIML (203 Czech Republic, guarantor)
Edition
Nature, Lodon, UK, Nature Publishing Group, 2009, 0028-0836
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
Genetics and molecular biology
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 34.480
RIV identification code
RIV/00216224:14310/09:00028676
Organization unit
Faculty of Science
UT WoS
000267636700045
Keywords (in Czech)
auxin; PIN5; polar auxin transport; endoplasmic reticulum; subcellular homeostasis
Keywords in English
auxin; PIN5; polar auxin transport; endoplasmic reticulum; subcellular homeostasis
Změněno: 3/12/2009 16:18, Mgr. Gabriela Jalová
V originále
The plant signalling molecule auxin provides positional information in a variety of developmental processes by means of its differential distribution (gradients) within plant tissues. Thus, cellular auxin levels often determine the developmental output of auxin signalling. Conceptually, transmembrane transport and metabolic processes regulate the steady-state levels of auxin in any given cell. In particular, PIN auxin-efflux-carrier-mediated, directional transport between cells is crucial for generating auxin gradients. Here we show that Arabidopsis thaliana PIN5, an atypical member of the PIN gene family, encodes a functional auxin transporter that is required for auxin-mediated development. PIN5 does not have a direct role in cell-to-cell transport but regulates intracellular auxin homeostasis and metabolism. PIN5 localizes, unlike other characterized plasma membrane PIN proteins, to endoplasmic reticulum (ER), presumably mediating auxin flow from the cytosol to the lumen of the ER. The ER localization of other PIN5-like transporters (including the moss PIN) indicates that the diversification of PIN protein functions in mediating auxin homeostasis at the ER, and cell-to-cell auxin transport at the plasma membrane, represent an ancient event during the evolution of land plants.
In Czech
The plant signalling molecule auxin provides positional information in a variety of developmental processes by means of its differential distribution (gradients) within plant tissues. Thus, cellular auxin levels often determine the developmental output of auxin signalling. Conceptually, transmembrane transport and metabolic processes regulate the steady-state levels of auxin in any given cell. In particular, PIN auxin-efflux-carrier-mediated, directional transport between cells is crucial for generating auxin gradients. Here we show that Arabidopsis thaliana PIN5, an atypical member of the PIN gene family, encodes a functional auxin transporter that is required for auxin-mediated development. PIN5 does not have a direct role in cell-to-cell transport but regulates intracellular auxin homeostasis and metabolism. PIN5 localizes, unlike other characterized plasma membrane PIN proteins, to endoplasmic reticulum (ER), presumably mediating auxin flow from the cytosol to the lumen of the ER. The ER localization of other PIN5-like transporters (including the moss PIN) indicates that the diversification of PIN protein functions in mediating auxin homeostasis at the ER, and cell-to-cell auxin transport at the plasma membrane, represent an ancient event during the evolution of land plants.
Links
| IAA601630703, research and development project |
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