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@article{863926, author = {Bednařík, Josef and Vlčková, Eva and Buršová, Šárka and Bělobrádková, Jana and Dušek, Ladislav and Sommer, Claudia}, article_location = {USA}, article_number = {3}, keywords = {etiology; painful sensory neuropathy; risk factors; small-fiber neuropathy}, language = {eng}, issn = {1085-9489}, journal = {Journal of the Peripheral Nervous System}, title = {Etiology of small-fiber neuropathy}, volume = {14}, year = {2009} }
TY - JOUR ID - 863926 AU - Bednařík, Josef - Vlčková, Eva - Buršová, Šárka - Bělobrádková, Jana - Dušek, Ladislav - Sommer, Claudia PY - 2009 TI - Etiology of small-fiber neuropathy JF - Journal of the Peripheral Nervous System VL - 14 IS - 3 SP - 177-183 EP - 177-183 PB - WILEY-BLACKWELL PUBLISHING SN - 10859489 KW - etiology KW - painful sensory neuropathy KW - risk factors KW - small-fiber neuropathy N2 - The aim was to evaluate the etiology in a group of 84 patients with painful sensory neuropathy with predominant small-fiber dysfunction(54 men,30 women,median:58; range:25-83 years).Involvement of small nerve fibers was verified by abnormal thermal thresholds and/or reduced intraepidermal nerve fiber densities.Motor signs or symptoms or significant clinical signs of sensory large-fiber involvement were exclusionary;33 patients,however,had sensory nerve conduction abnormalities.The multivariate regression model disclosed that diabetes mellitus(odds ratio [OR]=4.08),chronic alcoholism(OR=5.31),and serum cholesterol levels(OR=4.51)were the only parameters independently associated with small-fiber involvement.No possible etiology was detected in 19 patients(22.6%).In conclusion,the spectrum of risk factors and proportion of idiopathic cases in geographically defined small-fiber polyneuropathy sample is similar to that referred in large-fiber polyneuropathy. ER -
BEDNAŘÍK, Josef, Eva VLČKOVÁ, Šárka BURŠOVÁ, Jana BĚLOBRÁDKOVÁ, Ladislav DUŠEK and Claudia SOMMER. Etiology of small-fiber neuropathy. \textit{Journal of the Peripheral Nervous System}. USA: WILEY-BLACKWELL PUBLISHING, 2009, vol.~14, No~3, p.~177-183. ISSN~1085-9489.
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