J 2009

Dissociation, cognitive conflict and nonlinear patterns of heart rate dynamics in patients with unipolar depression

BOB, Petr, Marek ŠUSTA, Alica GREGUŠOVÁ and Denisa JAŠOVÁ

Basic information

Original name

Dissociation, cognitive conflict and nonlinear patterns of heart rate dynamics in patients with unipolar depression

Name in Czech

Disociace, kognitivní konflikt a nelineární vzorce v dynamice srdečního rytmu u pacientů s unipolární depresí

Authors

BOB, Petr (203 Czech Republic, guarantor, belonging to the institution), Marek ŠUSTA (203 Czech Republic), Alica GREGUŠOVÁ (203 Czech Republic) and Denisa JAŠOVÁ (203 Czech Republic)

Edition

Progress in Neuro-Psychopharmacology & Biological Psychiatry, USA, 2009, 0278-5846

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.823

RIV identification code

RIV/00216224:14110/09:00051264

Organization unit

Faculty of Medicine

DOI

UT WoS

000263212200025

Keywords (in Czech)

Chaos; kofnitivní konflikt; disociace; EKG; Lyapunův exponent; stres

Keywords in English

Chaos; cognitive conflict; dissociation; ECG; Lyapunov exponent; stress

Tags

International impact
Změněno: 10/4/2012 10:44, Mgr. Michal Petr

Abstract

ORIG CZ

V originále

Recent findings in cognitive neuroscience indicate that activation of anterior cingulate cortex (ACC) is related to detecting cognitive conflict. Conflict related ACC activation elicits responses in central autonomic network which can be assessed by psychophysiological measures such as heart rate variability (i.e. beat to beat R-R intervals - RRI). Recent findings in neuroscience also suggest that cognitive conflict is related to specific nonlinear chaotic changes of the signal generated by the neural systems. The present study used Stroop word-colour test as an experimental approach to the study of cognitive conflict in connection with RRI measurement, psychometric measurement of dissociation (DES) and calculation of largest Lyapunov exponents in nonlinear data analysis of RRI time series in 40 patients with unipolar depression and 35 healthy controls. Significant correlation 0.58 (p < 0.01) between largest Lyapunov exponents and DES found in depressive patients indicate that cognitive conflict related neural interference during conflicting Stroop task is closely related to dissociative processes. These results present first supportive evidence that degree of chaos could be related to dissociation.

In Czech

V práci byl u pacientů s unipolární depresí použit Stroopfův test se současnou nelineární analýzou R-R intervalů a psychometricky měřenou disociací jako experimentální přístup ke studiu kognitivního konfliktu

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
1M06039, research and development project
Name: Centrum pro neuropsychiatrický výzkum traumatického stresu
Investor: Ministry of Education, Youth and Sports of the CR