JANČÁLEK, Radim and Petr DUBOVÝ. Anatomical and Pathophysiological Aspects of Radicular Pain as a Basis for Therapeutic Strategies. In Acute Pain: Causes, Effects and Treatment. New York, USA: Nova Science Publishers, Inc, 2009, p. 243-263. Pain & Its Origins, Diagnosis & Treatments Series. ISBN 978-1-60741-223-6.
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Basic information
Original name Anatomical and Pathophysiological Aspects of Radicular Pain as a Basis for Therapeutic Strategies
Name in Czech Anatomický a patofyziologický aspekt radikulární bolesti jako základ pro strategii léčby
Authors JANČÁLEK, Radim (203 Czech Republic, belonging to the institution) and Petr DUBOVÝ (203 Czech Republic, guarantor, belonging to the institution).
Edition New York, USA, Acute Pain: Causes, Effects and Treatment, p. 243-263, 21 pp. Pain & Its Origins, Diagnosis & Treatments Series, 2009.
Publisher Nova Science Publishers, Inc
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study 30000 3. Medical and Health Sciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14110/09:00029804
Organization unit Faculty of Medicine
ISBN 978-1-60741-223-6
Keywords (in Czech) radikulární bolest; patofyzilogie
Keywords in English radicular pain; pathophysiology
Tags International impact, Reviewed
Changed by Changed by: prof. MUDr. Radim Jančálek, Ph.D., MBA, učo 152. Changed: 10/1/2012 23:48.
Abstract
Radicular pain (RP) is a common and debilitating clinical pain condition, the prevalence of which is estimated between 1% and 10%. The pathogenesis of RP was traditionally attributed to spinal root (SR) compression by a herniated disc. Although the mechanical concept is widely accepted, SR compression in itself does not seem to explain radiculopathy with pain. Thus, knowledge of the pathogenesis is precondition for successful treatment of RP.
Abstract (in Czech)
Radikulární bolest patří mezi bolestivé stavy, jehož prevalence se odhaduje na 1 až 10%. Patogeneze radikulární bolesti je tradičně spojována s kompresí spinálních kořenů výhřezem meziobratlové ploténky. Ačkoliv je tento mechanický koncept široce akceptovaný, nelze samotnou kompresí spinálních kořenů vysvětlit rozvoj radikulopatie s bolestí. Znalost patogeneze je tak předpokladem pro úspěšnou léčbu radikulárních bolestí.
Links
GA309/07/0121, research and development projectName: Změny cytokinů ve spinálních gangliích experimentálních modelů neuropatické bolesti indukované unilaterálním poškozením nervu
Investor: Czech Science Foundation, Spatio-temporal changes of cytokines in the dorsal root ganglia of experimental neuropathic pain models induced by unilateral nerve injury
MSM0021622404, plan (intention)Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
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