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@article{867575,
author = {Trifonov, Edward and Frenkel, Zakharia},
article_location = {London},
article_number = {3},
keywords = {Protein evolution; modular structure; protein sequence networks in sequence space},
language = {eng},
issn = {0959-440X},
journal = {Current Opinion in Structural Biology},
title = {Evolution of protein modularity},
volume = {19},
year = {2009}
}
TY - JOUR
ID - 867575
AU - Trifonov, Edward - Frenkel, Zakharia
PY - 2009
TI - Evolution of protein modularity
JF - Current Opinion in Structural Biology
VL - 19
IS - 3
SP - 335
EP - 335
PB - Elsevier Science Ltd.
SN - 0959440X
KW - Protein evolution
KW - modular structure
KW - protein sequence networks in sequence space
N2 - Proteins in their evolution follow several discrete stages, which is reflected in their modular organization. The sequences of the protein modules are highly variable while their functions and structures are rather conserved. The relatedness of the variable sequences is well represented by the networks in natural sequence space that also suggests evolutionary connections
ER -
TRIFONOV, Edward and Zakharia FRENKEL. Evolution of protein modularity. \textit{Current Opinion in Structural Biology}. London: Elsevier Science Ltd., 2009, vol.~19, No~3, p.~335-340. ISSN~0959-440X.
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