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@inbook{869298, author = {Dvořák, Petr}, address = {New York, USA}, booktitle = {Translational Stem Cell Research : Issues Beyond the Debate on the Moral Status of the Human Embyo}, editor = {Kristina Hug, Göran Hermerén}, keywords = {pluripotent stem cells; genetic diseases; therapy}, howpublished = {tištěná verze "print"}, language = {eng}, location = {New York, USA}, isbn = {978-1-60761-958-1}, pages = {65-76}, publisher = {Humana Press}, title = {Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells}, url = {http://www.springer.com/life+sciences/book/978-1-60761-958-1}, year = {2011} }
TY - CHAP ID - 869298 AU - Dvořák, Petr PY - 2011 TI - Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells VL - Stem Cell Biology and Regenerative Medicine PB - Humana Press CY - New York, USA SN - 9781607619581 KW - pluripotent stem cells KW - genetic diseases KW - therapy UR - http://www.springer.com/life+sciences/book/978-1-60761-958-1 N2 - For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. Translational Stem Cell Research is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma. Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications. ER -
DVOŘÁK, Petr. Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells. In Kristina Hug, Göran Hermerén. \textit{Translational Stem Cell Research : Issues Beyond the Debate on the Moral Status of the Human Embyo}. New York, USA: Humana Press, 2011, p.~65-76. Stem Cell Biology and Regenerative Medicine. ISBN~978-1-60761-958-1.
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