DVOŘÁK, Petr. Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells. In Kristina Hug, Göran Hermerén. Translational Stem Cell Research : Issues Beyond the Debate on the Moral Status of the Human Embyo. New York, USA: Humana Press, 2011, p. 65-76. Stem Cell Biology and Regenerative Medicine. ISBN 978-1-60761-958-1.
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Basic information
Original name Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells
Authors DVOŘÁK, Petr (752 Sweden, guarantor, belonging to the institution).
Edition New York, USA, Translational Stem Cell Research : Issues Beyond the Debate on the Moral Status of the Human Embyo, p. 65-76, 12 pp. Stem Cell Biology and Regenerative Medicine, 2011.
Publisher Humana Press
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study Genetics and molecular biology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
WWW URL
RIV identification code RIV/00216224:14110/11:00058852
Organization unit Faculty of Medicine
ISBN 978-1-60761-958-1
Keywords in English pluripotent stem cells; genetic diseases; therapy
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 2/4/2013 15:53.
Abstract
For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. Translational Stem Cell Research is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma. Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications.
Links
LC06034, research and development projectName: Regulace morfogeneze rostlinných buněk a orgánů
Investor: Ministry of Education, Youth and Sports of the CR, Regulation of morphogenesis of plant cells and organs
MSM0021622430, plan (intention)Name: Funkční a molekulární charakteristiky nádorových a normálních kmenových buněk - identifikace cílů pro nová terapeutika a terapeutické strategie
Investor: Ministry of Education, Youth and Sports of the CR, Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies
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