VRTĚLOVÁ, Pavlína, Oldřich COUFAL, Tomáš PAVLÍK, Marek BAŽOUT and Vuk FAIT. Viditelnost na ultrasonografii jako nejsilnější prediktor invazivity u duktálních karcinomů in situ v retrospektivní studii (Visibility in ultrasonography as the strongest invasion predictor in ductal carcinoma in situ in a retrospective study). Klinická onkologie. 2009, vol. 22, No 6, p. 278-283, 5 pp. ISSN 0862-495X.
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Basic information
Original name Viditelnost na ultrasonografii jako nejsilnější prediktor invazivity u duktálních karcinomů in situ v retrospektivní studii
Name (in English) Visibility in ultrasonography as the strongest invasion predictor in ductal carcinoma in situ in a retrospective study
Authors VRTĚLOVÁ, Pavlína, Oldřich COUFAL, Tomáš PAVLÍK, Marek BAŽOUT and Vuk FAIT.
Edition Klinická onkologie, 2009, 0862-495X.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Medicine
Keywords in English breast carcinoma; DCIS; sentinel lymph node biopsy; prediction; lymph node dissection
Tags Reviewed
Changed by Changed by: MUDr. Pavlína Krésová, Ph.D., učo 20379. Changed: 17/9/2011 23:11.
Abstract
Cílem této studie bylo zjistit podíl invazivních karcinomů v naší skupině pacientek operovaných pro DCIS, analyzovat prediktivní faktory invazivity a stanovit četnost nálezu uzlinových metastáz. Primární biopsii sentinelové uzliny doporučujeme v případě DCIS jednoznačně ultrasonograficky detekovatelných a u pacientek léčených totální mastektomií, u nichž by při nálezu invazivního karcinomu byla následná identifikace sentinelové uzliny obtížná.
Abstract (in English)
Detection of ductal carcinoma in situ (DCIS) of the breast has markedly increased since the introduction of screening mammography. Current management of this preinvasive lesion comprises complete margin-free resection of the tumour. Lymph node staging is still not indicated as a standard procedure but we can find published cases of pure DCIS with lymph node involvement as well as a high proportion of invasive carcinomas in the final histopathology. The aim of this study was to determine the proportion of invasive tumours in our group of patients operated on for DCIS, to analyse the predictive factors of invasion and to assess the frequency of lymph node metastases. We recommend performing primary sentinel node biopsy in DCIS unambiguously detected by ultrasound and in patients treated by total mastectomy where, in the case of invasive carcinoma, subsequent identification of the sentinel node would be difficult.
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