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@misc{870637,
author = {Altmannová, Veronika and Eckertboulet, Nadine and Arneric, Milica and Kolesár, Peter and Zhao, Xiaolan and Lisby, Michael and Krejčí, Lumír},
keywords = {Rad52; sumoylation; homologous recombination},
language = {eng},
title = {Rad52 Sumoylation Affects the Efficiency of the Recombination and DNA Repair},
url = {www.embo.org},
year = {2009}
}
TY - GEN
ID - 870637
AU - Altmannová, Veronika - Eckertboulet, Nadine - Arneric, Milica - Kolesár, Peter - Zhao, Xiaolan - Lisby, Michael - Krejčí, Lumír
PY - 2009
TI - Rad52 Sumoylation Affects the Efficiency of the Recombination and DNA Repair
KW - Rad52
KW - sumoylation
KW - homologous recombination
UR - www.embo.org
L2 - www.embo.org
N2 - Homologous recombination (HR) plays a vital role in DNA metabolic processes including meiosis, DNA repair, DNA replication, and maintenance of rDNA homeostasis. Defects in HR can lead to pathological outcomes, including genetic diseases and cancer. Recent studies suggest that the post-translational modification by small ubiquitin-like modifier (SUMO) protein plays an important role in mitotic and meiotic recombination but its precise function is still unclear. We will present the characterization of the novel effect of SUMOylation on the properties of Saccharomyces cerevisiae mediator protein Rad52.
ER -
ALTMANNOVÁ, Veronika, Nadine ECKERTBOULET, Milica ARNERIC, Peter KOLESÁR, Xiaolan ZHAO, Michael LISBY and Lumír KREJČÍ. \textit{Rad52 Sumoylation Affects the Efficiency of the Recombination and DNA Repair}. 2009.
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