| KROUPA, Radek, Aleš HEP, Jiří DOLINA, Vlastimil VÁLEK, Zuzana MATYÁŠOVÁ, Jitka PROKEŠOVÁ, Jaroslav SEDMÍK and Ivo NOVOTNÝ. Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results. Diseases of the Esophagus. Wiley blackwell, 2010, vol. 23, No 2, p. 100-105. ISSN 1120-8694. |
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@article{871629,
author = {Kroupa, Radek and Hep, Aleš and Dolina, Jiří and Válek, Vlastimil and Matyášová, Zuzana and Prokešová, Jitka and Sedmík, Jaroslav and Novotný, Ivo},
article_number = {2},
keywords = {achalasia - botulinum toxin- pneumatic dilatatation- therapy},
language = {eng},
issn = {1120-8694},
journal = {Diseases of the Esophagus},
title = {Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results},
volume = {23},
year = {2010}
}
TY - JOUR
ID - 871629
AU - Kroupa, Radek - Hep, Aleš - Dolina, Jiří - Válek, Vlastimil - Matyášová, Zuzana - Prokešová, Jitka - Sedmík, Jaroslav - Novotný, Ivo
PY - 2010
TI - Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results
JF - Diseases of the Esophagus
VL - 23
IS - 2
SP - 100-105
EP - 100-105
PB - Wiley blackwell
SN - 11208694
KW - achalasia - botulinum toxin- pneumatic dilatatation- therapy
N2 - Injection of botulinum toxin (BT) and pneumatic dilatation are available methods in nonsurgical treatment of achalasia. Authors anticipate beneficial effect of prior BT injection on the success of pneumatic dilatation and duration of its effect. There are no long-term data available to assess efficacy of combined treatment.Result of prospective study on 51 consecutive patients treated by comination method are presented. The cumulative 5 years remission rate in combined treated patients 69% was higher than in controls 50%; however it, was not statistically significant (P = 0.07). Eight patients (17%) with relapse of dysphagia were referred to laparoscopic Heller myotomy with no surgical complication.Initial injection of BT followed by PD seems to be effective for long-term results with fewer complications. But the combined therapy is not significantly superior to PD alone.
ER -
KROUPA, Radek, Aleš HEP, Jiří DOLINA, Vlastimil VÁLEK, Zuzana MATYÁŠOVÁ, Jitka PROKEŠOVÁ, Jaroslav SEDMÍK and Ivo NOVOTNÝ. Combined treatment of achalasia - botulinum toxin injection followed by pneumatic dilatation: long-term results. \textit{Diseases of the Esophagus}. Wiley blackwell, 2010, vol.~23, No~2, p.~100-105. ISSN~1120-8694.
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