KUBÍČEK, Karel, Jordan MONNET, Simone SCINTILLA, Jana KOPEČNÁ, Fabio ARNESANO, Lukáš TRANTÍREK, Claude CHOPARD, Giovanni NATILE and Jiří KOZELKA. Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex. Chemistry - An Asian Journal. WILEY-V C H VERLAG GMBH, 2010, vol. 5, No 2, p. 244-247. ISSN 1861-4728. |
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@article{873033, author = {Kubíček, Karel and Monnet, Jordan and Scintilla, Simone and Kopečná, Jana and Arnesano, Fabio and Trantírek, Lukáš and Chopard, Claude and Natile, Giovanni and Kozelka, Jiří}, article_number = {2}, keywords = {DNA structures; interstrand crosslinks; molecular modeling; NMR spectroscopy; platinum}, language = {eng}, issn = {1861-4728}, journal = {Chemistry - An Asian Journal}, title = {Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex}, url = {http://dx.doi.org/10.1002/asia.200900655}, volume = {5}, year = {2010} }
TY - JOUR ID - 873033 AU - Kubíček, Karel - Monnet, Jordan - Scintilla, Simone - Kopečná, Jana - Arnesano, Fabio - Trantírek, Lukáš - Chopard, Claude - Natile, Giovanni - Kozelka, Jiří PY - 2010 TI - Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex JF - Chemistry - An Asian Journal VL - 5 IS - 2 SP - 244-247 EP - 244-247 PB - WILEY-V C H VERLAG GMBH SN - 18614728 KW - DNA structures KW - interstrand crosslinks KW - molecular modeling KW - NMR spectroscopy KW - platinum UR - http://dx.doi.org/10.1002/asia.200900655 N2 - An unusual G6G11 interstrand crosslink is formed by spontaneous rearrangement of the canonical G5G6 intrastrand crosslink generated from the DNA duplex d(CCTTG5G6T7C8TC)-d(G11AGACCAAGG) and Pt(S,S-di-aminocyclohexane)2+ (the enantiomer of the antitumor drug oxaliplatin). The final product provides a rare example of intramolecular self-intercalation of DNA. ER -
KUBÍČEK, Karel, Jordan MONNET, Simone SCINTILLA, Jana KOPEČNÁ, Fabio ARNESANO, Lukáš TRANTÍREK, Claude CHOPARD, Giovanni NATILE and Jiří KOZELKA. Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex. \textit{Chemistry - An Asian Journal}. WILEY-V C H VERLAG GMBH, 2010, vol.~5, No~2, p.~244-247. ISSN~1861-4728.
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