Colicin E1 production is associated with bacteriocin multiproducer strains in uropathogenic Escherichia coli.

ŠMAJS, David, Lenka MICENKOVÁ, Jan ŠMARDA, M. VRBA, A. ŠEVČÍKOVÁ, Zuzana VALIŠOVÁ and Vladana WOZNICOVÁ. Colicin E1 production is associated with bacteriocin multiproducer strains in uropathogenic Escherichia coli. In III. International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2009). 2009.

Basic information

• Original name: Colicin E1 production is associated with bacteriocin multiproducer strains in uropathogenic Escherichia coli.
• Authors: ŠMAJS, David, Lenka MICENKOVÁ, Jan ŠMARDA, M. VRBA, A. ŠEVČÍKOVÁ, Zuzana VALIŠOVÁ and Vladana WOZNICOVÁ.
• Edition: III. International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2009), 2009.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 10600 1.6 Biological sciences
• Country of publisher: Portugal
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Organization unit: Faculty of Medicine
• Keywords in English: bacteriocin; colicin; microcin; uropathogenic E. coli strain

Abstract

The incidence of 29 bacteriocin types were tested in a group of 377 E. coli strains isolated from urinary tract infections (UTI) and in 413 control strains isolated from feces of patients without bacterial gut infection. The spectrum and frequency of individual bacteriocin types in the UTI strains was very similar to the control strains, probably reflecting the origin of UTI strains in the human gut. In the group of E. coli UTI strains, 159 bacteriocin producing strains (42.2%) were identified being not significantly different from 199 bacteriocin producers in the control group (48.2%). Producers with 3 and more identified bacteriocin types were more frequent in the UTI group. In the UTI strains, there is a marked increase of strains producing colicin E1 when compared to control (14.3% and 6.8%, respectively, p = 0.002). Moreover, this tendency is associated with multiproducers. There is a tendency in the UTI strains to possess additional genetic determinants and to synthesize colicin E1.

Links

• MSM0021622415, plan (intention): Name: Molekulární podstata buněčných a tkáňových regulací

Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations

• NS9665, research and development project: Name: Molekulární typizace bakteriocinů produkovaných kmeny Escherichia coli z klinického materiálu: identifikace kolicinů a mikrocinů v souborech komensálních a patogenních kmenů

Investor: Ministry of Health of the CR