SOUCKOVA, E., A. KOVARIK, Ladislav DUŠEK, L. HUMPOLIKOVA-ADAMKOVA, L. LAUEROVA and E. KREJCI. Reduced inducibility of SOCS3 by interferon gamma associates with higher resistance of human breast cancer lines as compared to normal mammary epithelial cells. Neoplasma. 2009, vol. 56, No 5, 8 pp. ISSN 0028-2685. |
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@article{874065, author = {Souckova, E. and Kovarik, A. and Dušek, Ladislav and HumpolikovaandAdamkova, L. and Lauerova, L. and Krejci, E.}, article_number = {5}, keywords = {suppressor of STAT signaling; STAT1; breast cancer; interferon; cell resistance}, language = {eng}, issn = {0028-2685}, journal = {Neoplasma}, title = {Reduced inducibility of SOCS3 by interferon gamma associates with higher resistance of human breast cancer lines as compared to normal mammary epithelial cells}, volume = {56}, year = {2009} }
TY - JOUR ID - 874065 AU - Souckova, E. - Kovarik, A. - Dušek, Ladislav - Humpolikova-Adamkova, L. - Lauerova, L. - Krejci, E. PY - 2009 TI - Reduced inducibility of SOCS3 by interferon gamma associates with higher resistance of human breast cancer lines as compared to normal mammary epithelial cells JF - Neoplasma VL - 56 IS - 5 SN - 00282685 KW - suppressor of STAT signaling KW - STAT1 KW - breast cancer KW - interferon KW - cell resistance N2 - The resistance to interferons (IFNs) limits their anticancer therapeutic efficacy. Here we studied the antiproliferative effect of interferon gamma in relation to SOCS3 expression in a panel of breast cancer cell lines and normal mammary epithelial cells. Compared to normal cells most breast cancer lines (7/8) were highly resistant to IFN-gamma. ER -
SOUCKOVA, E., A. KOVARIK, Ladislav DUŠEK, L. HUMPOLIKOVA-ADAMKOVA, L. LAUEROVA and E. KREJCI. Reduced inducibility of SOCS3 by interferon gamma associates with higher resistance of human breast cancer lines as compared to normal mammary epithelial cells. \textit{Neoplasma}. 2009, vol.~56, No~5, 8 pp. ISSN~0028-2685.
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