| HASOŇ, Stanislav, Vladimír VETTERL, František JELEN, Miroslav FOJTA, Soňa ŠTĚPÁNKOVÁ a Jan LATA. Sensitive Determination of Purine Derivatives in Human Urine by Electrochemical Methods. In 60th Annual Meeting of the Internationa Society of Electrochemistry, Peking University, Beijing, China, 16-21.8.2009, Book of Abstracts. Beijing, China: neuveden, 2009, 1 s. |
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@inproceedings{876033,
author = {Hasoň, Stanislav and Vetterl, Vladimír and Jelen, František and Fojta, Miroslav and Štěpánková, Soňa and Lata, Jan},
address = {Beijing, China},
booktitle = {60th Annual Meeting of the Internationa Society of Electrochemistry, Peking University, Beijing, China, 16-21.8.2009, Book of Abstracts},
keywords = {grinded carbon electrode; voltammetry; purine metabolism},
language = {eng},
location = {Beijing, China},
publisher = {neuveden},
title = {Sensitive Determination of Purine Derivatives in Human Urine by Electrochemical Methods.},
year = {2009}
}
TY - JOUR
ID - 876033
AU - Hasoň, Stanislav - Vetterl, Vladimír - Jelen, František - Fojta, Miroslav - Štěpánková, Soňa - Lata, Jan
PY - 2009
TI - Sensitive Determination of Purine Derivatives in Human Urine by Electrochemical Methods.
PB - neuveden
CY - Beijing, China
KW - grinded carbon electrode
KW - voltammetry
KW - purine metabolism
N2 - Using a mechanically grinded pyrolytic graphite electrode, a sensitive electrochemical method was developed for simultaneous determination of uric acid, xanthine, hypoxanthine (products of purine catabolism in human), allopurinol, and oxypurinol (a drug used in treatment of purine catabolism disorders ). It is demonstrated that differential pulse voltammetry in connection with this electrode can serve as a simple and efficient tool for monitoring transformation of purine catabolites catalyzed by xanthine oxidase as well as inhibition of this pathway by allopurinol being enzymatically converted to oxypurinol.
ER -
HASOŇ, Stanislav, Vladimír VETTERL, František JELEN, Miroslav FOJTA, Soňa ŠTĚPÁNKOVÁ a Jan LATA. Sensitive Determination of Purine Derivatives in Human Urine by Electrochemical Methods. In \textit{60th Annual Meeting of the Internationa Society of Electrochemistry, Peking University, Beijing, China, 16-21.8.2009, Book of Abstracts}. Beijing, China: neuveden, 2009, 1 s.
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