Comparison of Preventive and Therapeutic Transplantations of
Allogeneic Mesenchymal Stem Cells in the Healing of the Distal
Femoral Growth Plate Cartilage Defects in Miniature Pigs

J 2009

Comparison of Preventive and Therapeutic Transplantations of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs

PLÁNKA, Ladislav, David STARÝ, Jana HLUČILOVÁ, Jiří KLÍMA, Josef JANČÁŘ et. al.

Basic information

Original name

Comparison of Preventive and Therapeutic Transplantations of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs

Name in Czech

Srovnání preventivní a léčebné transplantace alogenních MSCs v léčbě defktu růstové ploténky distální části stehenní kosti u miniaturního prasete

Authors

PLÁNKA, Ladislav (203 Czech Republic, guarantor), David STARÝ (203 Czech Republic), Jana HLUČILOVÁ (203 Czech Republic), Jiří KLÍMA (203 Czech Republic), Josef JANČÁŘ (203 Czech Republic), Leoš KŘEN (203 Czech Republic), Jana LORENZOVÁ (203 Czech Republic), Lucie URBANOVÁ (203 Czech Republic), Michal CRHA (203 Czech Republic), Robert SRNEC (203 Czech Republic), Milan DVOŘÁK (203 Czech Republic), Petr GÁL (203 Czech Republic) and Alois NEČAS (203 Czech Republic)

Edition

Acta Veterinaria, Brno, 2009, 0001-7213

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30211 Orthopaedics

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.403

RIV identification code

RIV/00216224:14110/09:00039555

Organization unit

Faculty of Medicine

UT WoS

000267788000015

Keywords in English

MSCs; growth plate; deformity; bone bridge

Změněno: 23/3/2010 20:30, prof. MUDr. Ladislav Plánka, Ph.D.

Abstract

ORIG CZ

V originále

Preventive transplantation of allogeneic MSCs into the defect of the distal growth zone of femur appears more suitable compared to the therapeutic transplantation, with regard to the more pronounced lengthwise bone growth. Differences found in the extent of valgus deformity were non-significant comparing preventive and therapeutic transplantations of MSCs.

In Czech

Preventivní transplantace alogenních MSCs do defektu distální růstové zóny femuru se jeví vhodnější v porovnání s terapeutickou transplantací vzhledem k výraznějšímu růstu kosti do délky. Rozdíly zjištěné v rozsahu valgózní deformity nebyly při srovnání preventivní a terapeutické transplantace MSCs signifikantní.

Links

NR9296, research and development project

Name: Využití kmenových buněk k léčbě poraněné růstové ploténky na modelu miniaturních prasat - experimentální studie.

2B06130, research and development project

Name: Využití nově syntetizovaných biomateriálů v kombinaci s kmenovými buňkami v léčbě chorob, které postihují lidské tkáně derivované z mesodermu: chrupavku, kost, vazy a menisky. (Acronym: Chondros)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

PLÁNKA, Ladislav, David STARÝ, Jana HLUČILOVÁ, Jiří KLÍMA, Josef JANČÁŘ, Leoš KŘEN, Jana LORENZOVÁ, Lucie URBANOVÁ, Michal CRHA, Robert SRNEC, Milan DVOŘÁK, Petr GÁL and Alois NEČAS. Comparison of Preventive and Therapeutic Transplantations of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs. Acta Veterinaria. Brno, 2009, vol. 78, No 2, p. 293-302. ISSN 0001-7213.

@article{877012,
   author = {Plánka, Ladislav and Starý, David and Hlučilová, Jana and Klíma, Jiří and Jančář, Josef and Křen, Leoš and Lorenzová, Jana and Urbanová, Lucie and Crha, Michal and Srnec, Robert and Dvořák, Milan and Gál, Petr and Nečas, Alois},
   article_location = {Brno},
   article_number = {2},
   keywords = {MSCs; growth plate; deformity; bone bridge},
   language = {eng},
   issn = {0001-7213},
   journal = {Acta Veterinaria},
   title = {Comparison of Preventive and Therapeutic Transplantations of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs},
   volume = {78},
   year = {2009}
}

TY  - JOUR
ID  - 877012
AU  - Plánka, Ladislav - Starý, David - Hlučilová, Jana - Klíma, Jiří - Jančář, Josef - Křen, Leoš - Lorenzová, Jana - Urbanová, Lucie - Crha, Michal - Srnec, Robert - Dvořák, Milan - Gál, Petr - Nečas, Alois
PY  - 2009
TI  - Comparison of Preventive and Therapeutic Transplantations of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs
JF  - Acta Veterinaria
VL  - 78
IS  - 2
SP  - 293-302
EP  - 293-302
SN  - 00017213
KW  - MSCs
KW  - growth plate
KW  - deformity
KW  - bone bridge
N2  - Preventive transplantation of allogeneic MSCs into the defect of the distal growth zone of femur appears more suitable compared to the therapeutic transplantation, with regard to the more pronounced lengthwise bone growth. Differences found in the extent of valgus deformity were non-significant comparing preventive and therapeutic transplantations of MSCs.
ER  -

PLÁNKA, Ladislav, David STARÝ, Jana HLUČILOVÁ, Jiří KLÍMA, Josef JANČÁŘ, Leoš KŘEN, Jana LORENZOVÁ, Lucie URBANOVÁ, Michal CRHA, Robert SRNEC, Milan DVOŘÁK, Petr GÁL and Alois NEČAS. Comparison of Preventive and Therapeutic Transplantations of Allogeneic Mesenchymal Stem Cells in the Healing of the Distal Femoral Growth Plate Cartilage Defects in Miniature Pigs. \textit{Acta Veterinaria}. Brno, 2009, vol.~78, No~2, p.~293-302. ISSN~0001-7213.

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