| CRHA, Michal, Alois NEČAS, Robert SRNEC, Jan JANOVEC, Ladislav STEHLIK, Petr RAUŠER, Lucie URBANOVÁ, Ladislav PLÁNKA, Josef JANČÁŘ and Evžen AMLER. Mesenchymal Stem Cells in Bone Tissue Regeneration and Application. Acta Veterinaria. Brno, 2009, vol. 78, No 4, p. 635-642. ISSN 0001-7213. |
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@article{877017,
author = {Crha, Michal and Nečas, Alois and Srnec, Robert and Janovec, Jan and Stehlik, Ladislav and Raušer, Petr and Urbanová, Lucie and Plánka, Ladislav and Jančář, Josef and Amler, Evžen},
article_location = {Brno},
article_number = {4},
keywords = {Tissue engineering; biomaterials; scaffold; segmental bone lesion; fracture healing; growth},
language = {eng},
issn = {0001-7213},
journal = {Acta Veterinaria},
title = {Mesenchymal Stem Cells in Bone Tissue Regeneration and Application},
volume = {78},
year = {2009}
}
TY - JOUR
ID - 877017
AU - Crha, Michal - Nečas, Alois - Srnec, Robert - Janovec, Jan - Stehlik, Ladislav - Raušer, Petr - Urbanová, Lucie - Plánka, Ladislav - Jančář, Josef - Amler, Evžen
PY - 2009
TI - Mesenchymal Stem Cells in Bone Tissue Regeneration and Application
JF - Acta Veterinaria
VL - 78
IS - 4
SP - 635-642
EP - 635-642
SN - 00017213
KW - Tissue engineering
KW - biomaterials
KW - scaffold
KW - segmental bone lesion
KW - fracture healing
KW - growth
N2 - This synoptic study gives a concise overview of current knowledge of bone healing, the role of mesenchymal stem cells in bone tissue regeneration and contemporary possibilities of supporting regeneration of damaged bone. Attention of research concerning the healing of fractures with extensive loss of bone tissue following trauma, the treatment of belatedly healing or non-healing fractures or the healing of segmental bone defects following tumour resection, is focused on development of three-dimensional scaffolds planted with mesenchymal stem cells that might be used for reconstruction of such large bone lesions. Presented are possibilities of transplantation of mesenchymal stem cells combined with biomaterials into bone defects, including the results of our own experimental studies dealing with the use of stem cells in the treatment of damaged tissues of the musculoskeletal system in animal models.
ER -
CRHA, Michal, Alois NEČAS, Robert SRNEC, Jan JANOVEC, Ladislav STEHLIK, Petr RAUŠER, Lucie URBANOVÁ, Ladislav PLÁNKA, Josef JANČÁŘ and Evžen AMLER. Mesenchymal Stem Cells in Bone Tissue Regeneration and Application. \textit{Acta Veterinaria}. Brno, 2009, vol.~78, No~4, p.~635-642. ISSN~0001-7213.
|
