Detailed Information on Publication Record
2009
Interaction of Cytidine 5 '-Monophosphate with Au(111): An In Situ Infrared Spectroscopic Study
DONEUX, Thomas and Lukáš FOJTBasic information
Original name
Interaction of Cytidine 5 '-Monophosphate with Au(111): An In Situ Infrared Spectroscopic Study
Authors
DONEUX, Thomas and Lukáš FOJT
Edition
ChemPhysChem, Weinheim, WILEY-VCH Verlag GmbH & Co. KGaA, 2009, 1439-4235
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10610 Biophysics
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 3.453
Organization unit
Faculty of Medicine
UT WoS
000267928100043
Keywords in English
chemisorption; electrochemistry; interfaces; IR spectroscopy; nucleobases
Tags
Tags
International impact, Reviewed
Změněno: 24/3/2010 10:41, Mgr. Lukáš Fojt, Ph.D.
Abstract
V originále
The interaction of cytidine 5-monophosphate (CMP) with gold surfaces is studied by means of in situ infrared spectroscopy and cyclic voltammetry at the Au(111)/aqueous solution interface.Similar to other nucleic acid components, cytidine 5-monophosphate is chemisorbed on the surface at positive potentials, and the amount of adsorbed CMP increases with the potential. Subtractively normalized interfacial Fourier-transform infrared spectroscopy (SNIFTIRS) is used to identify the adsorbed and desorbed species. Upon electrochemical desorption, the molecules released in solution are unprotonated on the N3 atom. Striking similarities are found between the spectrum of adsorbed CMP and the solution spectrum of protonated CMP. The origin of such similarities is discussed. The results strongly suggest that chemisorption occurs through the N3 atom of the pyrimidine ring. A comparison is drawn with cytidine, whose electrochemical and spectroscopic behaviors are also investigated.