VAŇÁČOVÁ, Štěpánka. Distinct Roles of TRAMP complexes in yeast RNA Metabolism. In Messenger RNA 3' ends and gene expression - EMBO workshop. 2009.
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Basic information
Original name Distinct Roles of TRAMP complexes in yeast RNA Metabolism
Name in Czech Distinct Roles of TRAMP complexes in yeast RNA Metabolism
Authors VAŇÁČOVÁ, Štěpánka.
Edition Messenger RNA 3' ends and gene expression - EMBO workshop, 2009.
Other information
Original language English
Type of outcome Conference abstract
Field of Study Genetics and molecular biology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Organization unit Faculty of Science
Keywords in English Messenger RNA 3 prime end formation provides a clear paradigm for such an interconnection point as it represents the cross-over between transcribing a gene and translating its messenger RNA.
Tags International impact
Changed by Changed by: prof. Mgr. Štěpánka Vaňáčová, Ph.D., učo 105562. Changed: 9/4/2010 10:56.
Abstract
The scientific programme for this Oxford EMBO workshop started with gene transcription, how the chromatin template is made ready for transcription and how the end of the gene is connected to its beginning. This transcription focus will then lead into how processing of the initial pre-mRNA is coupled to transcription, both splicing, but more importantly 3 end processing of: histone, polyA+ mRNAs, small stable RNAs (snRNA and snoRNA) and cryptic unstable RNAs (CUTs). Following nuclear export, mRNA translation is also intimately coupled to the appropriate structure of its 3 end, be this the polyA tail or a hairpin as in histone mRNA. The final critical stage in gene expression is the regulation of mRNA turn over, again closely connected to the integrity of the polyA tail. Superimposed on this whole process of gene expression is a surveillance process that acts at all stages.
Abstract (in Czech)
The scientific programme for this Oxford EMBO workshop started with gene transcription, how the chromatin template is made ready for transcription and how the end of the gene is connected to its beginning. This transcription focus will then lead into how processing of the initial pre-mRNA is coupled to transcription, both splicing, but more importantly 3 end processing of: histone, polyA+ mRNAs, small stable RNAs (snRNA and snoRNA) and cryptic unstable RNAs (CUTs). Following nuclear export, mRNA translation is also intimately coupled to the appropriate structure of its 3 end, be this the polyA tail or a hairpin as in histone mRNA. The final critical stage in gene expression is the regulation of mRNA turn over, again closely connected to the integrity of the polyA tail. Superimposed on this whole process of gene expression is a surveillance process that acts at all stages.
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