| ŠMEJKAL, Karel, Tereza ŠLAPETOVÁ, Pavel KRMENČÍK, Renata KUBÍNOVÁ, Pavel SUCHÝ, Stefano DALLACQUA, Gabbriella INNOCENTI, Ján VANČO, Karolína KALVAROVÁ, Margita DVORSKÁ, Jiří SLANINA, Eva KRAMÁŘOVÁ, Jan MUSELÍK a Milan ŽEMLIČKA. Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models. Molecules. Basel: MDPI, 2010, roč. 15, č. 3, s. 1223-1231. ISSN 1420-3049. |
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@article{878516,
author = {Šmejkal, Karel and Šlapetová, Tereza and Krmenčík, Pavel and Kubínová, Renata and Suchý, Pavel and DallAcqua, Stefano and Innocenti, Gabbriella and Vančo, Ján and Kalvarová, Karolína and Dvorská, Margita and Slanina, Jiří and Kramářová, Eva and Muselík, Jan and Žemlička, Milan},
article_location = {Basel},
article_number = {3},
keywords = {Schisandra chinensis; dibenzocyclooctadiene lignans; antiradical; diabetes mellitus},
language = {eng},
issn = {1420-3049},
journal = {Molecules},
title = {Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models},
volume = {15},
year = {2010}
}
TY - JOUR
ID - 878516
AU - Šmejkal, Karel - Šlapetová, Tereza - Krmenčík, Pavel - Kubínová, Renata - Suchý, Pavel - DallAcqua, Stefano - Innocenti, Gabbriella - Vančo, Ján - Kalvarová, Karolína - Dvorská, Margita - Slanina, Jiří - Kramářová, Eva - Muselík, Jan - Žemlička, Milan
PY - 2010
TI - Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models
JF - Molecules
VL - 15
IS - 3
SP - 1223-1231
EP - 1223-1231
PB - MDPI
SN - 14203049
KW - Schisandra chinensis
KW - dibenzocyclooctadiene lignans
KW - antiradical
KW - diabetes mellitus
N2 - The in vitro antiradical activity of Schisandra chinensis lignans was investigated using DPPH, ABTS, Fenton reaction inhibition and tyrosine-nitration inhibition assays, as were the in vivo antidiabetic activities of selected lignans in an animal model of alloxaninduced diabetes. Different degrees of antiradical activity were found, depending upon the structural parameters of the tested compounds. Unfortunately, the compounds showed no antidiabetic activity in concentration range tested.
ER -
ŠMEJKAL, Karel, Tereza ŠLAPETOVÁ, Pavel KRMENČÍK, Renata KUBÍNOVÁ, Pavel SUCHÝ, Stefano DALLACQUA, Gabbriella INNOCENTI, Ján VANČO, Karolína KALVAROVÁ, Margita DVORSKÁ, Jiří SLANINA, Eva KRAMÁŘOVÁ, Jan MUSELÍK a Milan ŽEMLIČKA. Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models. \textit{Molecules}. Basel: MDPI, 2010, roč.~15, č.~3, s.~1223-1231. ISSN~1420-3049.
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