Portable capillary-based (non-chip) capillary electrophoresis

J 2010

Portable capillary-based (non-chip) capillary electrophoresis

RYVOLOVÁ, Markéta, Jan PREISLER, Dermot BRABAZON, and Miroslav MACKA

Basic information

Original name

Portable capillary-based (non-chip) capillary electrophoresis

Name in Czech

Přenosné kapilární (nečipové) elektroforézy

Authors

RYVOLOVÁ, Markéta (203 Czech Republic, belonging to the institution), Jan PREISLER (203 Czech Republic, guarantor, belonging to the institution), Dermot BRABAZON, (372 Ireland) and Miroslav MACKA (203 Czech Republic)

Edition

Trends in Analytical Chemistry, 2010, 0165-9936

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10406 Analytical chemistry

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 6.602

RIV identification code

RIV/00216224:14310/10:00043699

Organization unit

Faculty of Science

UT WoS

000276878500022

Keywords in English

Capillary electrophoresis (CE); Chemiluminescence detection (CLD); Electrochemical detection (ECD); Injection; Laser diode (LD); Lightemitting

Změněno: 9/4/2013 10:50, prof. Mgr. Jan Preisler, Ph.D.

Abstract

ORIG CZ

V originále

Miniaturized, portable instrumentation has been gaining popularity in all areas of analytical chemistry. Capillary electrophoresis (CE), due to its main strengths of high separation efficiency, relatively short analysis time and low consumption of chemicals, is a particularly suitable technique for use in portable analytical instrumentation. In line with the general trend in miniaturization in chemistry utilizing microfluidic chips, the main thrust of portable CE (P-CE) systems development is towards chip-based miniaturized CE. Despite this, capillary-based (non-chip) P-CE systems have certain unmatched advantages, especially in the relative simplicity of the regular cylindrical geometry of the CE capillary, maximal volume-to-surface ratio, no need to design and to fabricate a chip, the low costs of capillary compared to chip, and better performance with some detection techniques. This review presents an overview of the state of the art of P-CE and literature relevant to future developments. We pay particular attention to the development and the potential of miniaturization of functional parts for P-CE. These include components related to sample introduction, separation and detection, which are the key elements in P-CE design. The future of P-CE may be in relatively simple, rugged designs (e.g., using a short piece of capillary fixed to a chip-sized platform on which injection and detection parts can be mounted). Electrochemical detection is well suited for miniaturization, so is probably the most suitable detection technique for P-CE, but optical detection is gaining interest, especially due to miniaturized light sources (e.g., light emitting diodes).

In Czech

Abstrakt titulu Přenosné kapilární (nečipové) elektroforézy viz anglická verze

Links

GA203/09/1025, research and development project

Name: Multidetekční platforma pro mikrokolonové separace proteinů a peptidů

Investor: Czech Science Foundation, Multidetection platform for microcolumn separation of proteins and peptides

MSM0021622415, plan (intention)

Name: Molekulární podstata buněčných a tkáňových regulací

Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations

Citovat

RYVOLOVÁ, Markéta, Jan PREISLER, Dermot BRABAZON, and Miroslav MACKA. Portable capillary-based (non-chip) capillary electrophoresis. Trends in Analytical Chemistry. 2010, vol. 29, No 4, p. 339-353, 14 pp. ISSN 0165-9936.

@article{879296,
   author = {Ryvolová, Markéta and Preisler, Jan and Brabazon,, Dermot and Macka, Miroslav},
   article_number = {4},
   keywords = {Capillary electrophoresis (CE); Chemiluminescence detection (CLD); Electrochemical detection (ECD); Injection; Laser diode (LD); Lightemitting},
   language = {eng},
   issn = {0165-9936},
   journal = {Trends in Analytical Chemistry},
   title = {Portable capillary-based (non-chip) capillary electrophoresis},
   volume = {29},
   year = {2010}
}

TY  - JOUR
ID  - 879296
AU  - Ryvolová, Markéta - Preisler, Jan - Brabazon,, Dermot - Macka, Miroslav
PY  - 2010
TI  - Portable capillary-based (non-chip) capillary electrophoresis
JF  - Trends in Analytical Chemistry
VL  - 29
IS  - 4
SP  - 339-353
EP  - 339-353
SN  - 01659936
KW  - Capillary electrophoresis (CE)
KW  - Chemiluminescence detection (CLD)
KW  - Electrochemical detection (ECD)
KW  - Injection
KW  - Laser diode (LD)
KW  - Lightemitting
N2  - Miniaturized, portable instrumentation has been gaining popularity in all areas of analytical chemistry. Capillary electrophoresis (CE), due to its main strengths of high separation efficiency, relatively short analysis time and low consumption of chemicals, is a particularly suitable technique for use in portable analytical instrumentation. In line with the general trend in miniaturization in chemistry utilizing microfluidic chips, the main thrust of portable CE (P-CE) systems development is towards chip-based miniaturized CE. Despite this, capillary-based (non-chip) P-CE systems have certain unmatched advantages, especially in the relative simplicity of the regular cylindrical geometry of the CE capillary, maximal volume-to-surface ratio, no need to design and to fabricate a chip, the low costs of capillary compared to chip, and better performance with some detection techniques. This review presents an overview of the state of the art of P-CE and literature relevant to future developments. We pay particular attention to the development and the potential of miniaturization of functional parts for P-CE. These include components related to sample introduction, separation and detection, which are the key elements in P-CE design. The future of P-CE may be in relatively simple, rugged designs (e.g., using a short piece of capillary fixed to a chip-sized platform on which injection and detection parts can be mounted). Electrochemical detection is well suited for miniaturization, so is probably the most suitable detection technique for P-CE, but optical detection is gaining interest, especially due to miniaturized light sources (e.g., light emitting diodes).
ER  -

RYVOLOVÁ, Markéta, Jan PREISLER, Dermot BRABAZON, and Miroslav MACKA. Portable capillary-based (non-chip) capillary electrophoresis. \textit{Trends in Analytical Chemistry}. 2010, vol.~29, No~4, p.~339-353, 14 pp. ISSN~0165-9936.

Detailed Information on Publication Record