LINDQVIST, Maria, Zachi HORN, Vítězslav BRYJA, Gunnar SCHULTE, Panagiotis PAPACHRISTOU, Rieko AJIMA, Cecilia DYBERG, Ernest ARENAS, Terry P YAMAGUCHI, Hugo LAGERCRANTZ and Thomas RINGSTEDT. Vang-like protein 2 and Rac 1 interact to regulate adherens junctions. JOURNAL OF CELL SCIENCE. 2010, vol. 2010, No 123, p. 472-483. ISSN 0021-9533.
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Basic information
Original name Vang-like protein 2 and Rac 1 interact to regulate adherens junctions
Name in Czech Vangl2 a Rac-1 interakce vede k regulaci adhezivních spojení
Authors LINDQVIST, Maria (752 Sweden), Zachi HORN (376 Israel), Vítězslav BRYJA (203 Czech Republic, guarantor, belonging to the institution), Gunnar SCHULTE (276 Germany), Panagiotis PAPACHRISTOU (300 Greece), Rieko AJIMA (840 United States of America), Cecilia DYBERG (752 Sweden), Ernest ARENAS (724 Spain), Terry P YAMAGUCHI (840 United States of America), Hugo LAGERCRANTZ (752 Sweden) and Thomas RINGSTEDT (752 Sweden).
Edition JOURNAL OF CELL SCIENCE, 2010, 0021-9533.
Other information
Original language English
Type of outcome Article in a journal
Field of Study Genetics and molecular biology
Country of publisher Sweden
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 6.290
RIV identification code RIV/00216224:14310/10:00043738
Organization unit Faculty of Science
UT WoS 000274337800018
Keywords in English Cell adhesion; Neurulation; PCP; Wnt
Changed by Changed by: prof. Mgr. Vítězslav Bryja, Ph.D., učo 11088. Changed: 7/3/2011 11:33.
Abstract
The Wnt Planar Cell Polarity (PCP) pathway signals through small Rho-like GTPases to regulate the cytoskeleton. Here we investigate the function of the mammalian PCP protein Vangl2. We propose that Vangl2 affects cell adhesion and the cytoskeleton by recruiting Rac1 .
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MSM0021622430, plan (intention)Name: Funkční a molekulární charakteristiky nádorových a normálních kmenových buněk - identifikace cílů pro nová terapeutika a terapeutické strategie
Investor: Ministry of Education, Youth and Sports of the CR, Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies
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