SLOVÁČKOVÁ, Jana, Diana GROCHOVÁ, Jarmila NAVRÁTILOVÁ, Jan ŠMARDA and Jana ŠMARDOVÁ. Transactivation by temperature-dependent p53 mutants in yeast and human cells. Cell Cycle. LANDES BIOSCIENCE, USA, 2010, vol. 9, No 11, p. 1-8. ISSN 1538-4101. |
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@article{881209, author = {Slováčková, Jana and Grochová, Diana and Navrátilová, Jarmila and Šmarda, Jan and Šmardová, Jana}, article_number = {11}, keywords = {p53; FASAY; transactivation}, language = {eng}, issn = {1538-4101}, journal = {Cell Cycle}, title = {Transactivation by temperature-dependent p53 mutants in yeast and human cells}, volume = {9}, year = {2010} }
TY - JOUR ID - 881209 AU - Slováčková, Jana - Grochová, Diana - Navrátilová, Jarmila - Šmarda, Jan - Šmardová, Jana PY - 2010 TI - Transactivation by temperature-dependent p53 mutants in yeast and human cells JF - Cell Cycle VL - 9 IS - 11 SP - 1-8 EP - 1-8 PB - LANDES BIOSCIENCE, USA SN - 15384101 KW - p53 KW - FASAY KW - transactivation N2 - We analyzed transactivation of several p53-target genes by 23 temperature-dependent p53 mutants and stratified them into four functional groups. Seventeen mutants exhibited temperature-dependency and discriminative character in human and yeast cells. Our analysis showed that functional analysis of separated alleles in yeast is valuable tool for assessment of the human p53 status. ER -
SLOVÁČKOVÁ, Jana, Diana GROCHOVÁ, Jarmila NAVRÁTILOVÁ, Jan ŠMARDA and Jana ŠMARDOVÁ. Transactivation by temperature-dependent p53 mutants in yeast and human cells. \textit{Cell Cycle}. LANDES BIOSCIENCE, USA, 2010, vol.~9, No~11, p.~1-8. ISSN~1538-4101.
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