Cognitive deficit in schizophrenia and its remediation

PŘIKRYLOVÁ KUČEROVÁ, Hana, Helena FEJFAROVÁ, Petra BARTOŇOVÁ and Radovan PŘIKRYL. Cognitive deficit in schizophrenia and its remediation. In 2nd Scizophrenia International Research Society Conference. 2010. ISSN 0920-9964.

Basic information

• Original name: Cognitive deficit in schizophrenia and its remediation
• Name in Czech: Kognitivní deficit u schizofrenie a jeho remediace
• Name (in English): Cognitive deficit in schizophrenia and its remediation
• Authors: PŘIKRYLOVÁ KUČEROVÁ, Hana, Helena FEJFAROVÁ, Petra BARTOŇOVÁ and Radovan PŘIKRYL.
• Edition: 2nd Scizophrenia International Research Society Conference, 2010.

Other information

• Original language: Czech
• Type of outcome: Conference abstract
• Field of Study: 30000 3. Medical and Health Sciences
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• Impact factor: Impact factor: 4.374
• Organization unit: Faculty of Medicine
• ISSN: 0920-9964
• UT WoS: 000276936801350
• Keywords (in Czech): kognitivní deficit, remediace, schizofrenie
• Keywords in English: cognitive deficit, remediation, schizophrenia
• Tags: Reviewed

Abstract

Schizophrenia is a severe mental disorder characterized by a variety of signs and symptoms. Since its earliest conception as “dementia praecox“ (i.e. early onset dementia), impaired cognitive function has also been considered a core feature. Research into cognition and schizophrenia over the past years has recently been growing. Cognitive deficit is a virtually omni-present component of schizophrenic psychopathology, independent of other aspects of schizophrenia. It underlays other symptoms of schizophrenia and affects the success of therapy, ability of social adaptation and patients’ quality of life. Cognitive skills in schizophrenia predict social functioning and may serve as outcome measures in the development of effective treatment strategies. One of the possibilities of non-pharmacological improvement of cognitive function is remediation using computer rehabilitation software. It has been proved as an effective method. In our study we found global positive effect of aproximately bimonthly (20sessions) training of cognitive function in patients with schizophrenia using computer rehabilitation software PSS CogRehab. Except verbal fluency, which appears stationary during training of cognitive function, all others domains of cognitive function improved during rehabilitation using computer training of cognitive function. The biggest improvement we located in these domains: psychomotor speed, auditive reaction time and verbal learning and memory, where improvement in neuropsychological tests reached statistically significant difference.

Abstract (in English)

Schizophrenia is a severe mental disorder characterized by a variety of signs and symptoms. Since its earliest conception as “dementia praecox“ (i.e. early onset dementia), impaired cognitive function has also been considered a core feature. Research into cognition and schizophrenia over the past years has recently been growing. Cognitive deficit is a virtually omni-present component of schizophrenic psychopathology, independent of other aspects of schizophrenia. It underlays other symptoms of schizophrenia and affects the success of therapy, ability of social adaptation and patients’ quality of life. Cognitive skills in schizophrenia predict social functioning and may serve as outcome measures in the development of effective treatment strategies. One of the possibilities of non-pharmacological improvement of cognitive function is remediation using computer rehabilitation software. It has been proved as an effective method. In our study we found global positive effect of aproximately bimonthly (20sessions) training of cognitive function in patients with schizophrenia using computer rehabilitation software PSS CogRehab. Except verbal fluency, which appears stationary during training of cognitive function, all others domains of cognitive function improved during rehabilitation using computer training of cognitive function. The biggest improvement we located in these domains: psychomotor speed, auditive reaction time and verbal learning and memory, where improvement in neuropsychological tests reached statistically significant difference.

Links

• MSM0021622404, plan (intention): Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.