Aspergillus fumigatus lectins - how to stay in touch

HOUSER, Josef, Jan KOMÁREK, Nikola KOSTLÁNOVÁ, Gianluca CIOCCI, Anne IMBERTY and Michaela WIMMEROVÁ. Aspergillus fumigatus lectins - how to stay in touch (Aspergillus fumigatus lectins - how to stay in touch). In XIV.Setkání biochemiků a molekulárních biologů. 2010. ISBN 978-80-210-5164-5.

Basic information

• Original name: Aspergillus fumigatus lectins - how to stay in touch
• Name in Czech: Lektiny Aspergillus fumigatus - jak zůstat v kontaktu
• Name (in English): Aspergillus fumigatus lectins - how to stay in touch
• Authors: HOUSER, Josef (203 Czech Republic, belonging to the institution), Jan KOMÁREK (203 Czech Republic, belonging to the institution), Nikola KOSTLÁNOVÁ (203 Czech Republic, belonging to the institution), Gianluca CIOCCI (380 Italy), Anne IMBERTY (250 France) and Michaela WIMMEROVÁ (203 Czech Republic, guarantor, belonging to the institution).
• Edition: XIV.Setkání biochemiků a molekulárních biologů, 2010.

Other information

• Original language: Czech
• Type of outcome: Conference abstract
• Field of Study: 10600 1.6 Biological sciences
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14310/10:00044026
• Organization unit: Faculty of Science
• ISBN: 978-80-210-5164-5
• Keywords (in Czech): Aspergillus fumigatus lektin
• Keywords in English: Aspergillus fumigatus lectin

Abstract

Saprophytic fungus Aspergillus fumigatus is widespread alergen and an important pathogen for immunocompromised patients as well. Typical way, which many pathogens including Aspergillus utilize for binding to host-cells, is via sugar-binding proteins - lectins. In our research group we combine structural and functional approaches to precisely describe lectins' binding properties. Together with bioinformatics and molecular modeling we build up a complex picture of these biologicaly and medicaly important macromolecules.

Abstract (in English)

Saprophytic fungus Aspergillus fumigatus is widespread alergen and an important pathogen for immunocompromised patients as well. Typical way, which many pathogens including Aspergillus utilize for binding to host-cells, is via sugar-binding proteins - lectins. In our research group we combine structural and functional approaches to precisely describe lectins' binding properties. Together with bioinformatics and molecular modeling we build up a complex picture of these biologicaly and medicaly important macromolecules.

Links

• GA303/09/1168, research and development project: Name: Lektiny z lidských patogenů - struktura, funkce, inženýrství

Investor: Czech Science Foundation, Lectins from human pathogens - structure, function, engineering

• GD301/09/H004, research and development project: Name: Molekulární a strukturní biologie vybraných cytostatik. Od mechanistických studií k chemoterapii rakoviny

Investor: Czech Science Foundation

• LC06030, research and development project: Name: Biomolekulární centrum

Investor: Ministry of Education, Youth and Sports of the CR, Biomolecular centre

• ME08008, research and development project: Name: Návrh antibakteriálních a antivirových léků na bázi cukrů a glykomimetik

Investor: Ministry of Education, Youth and Sports of the CR, Design of Carbohydrates and Glycomimetics as Antibacterial and Antiviral Drugs, Research and Development Programme KONTAKT (ME)

• MSM0021622413, plan (intention): Name: Proteiny v metabolismu a při interakci organismů s prostředím

Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment