Detailed Information on Publication Record

HOLUBOVÁ, Sylvie, Přemysl LUBAL and Libuše TRNKOVÁ. SPECTROSCOPIC STUDY OF PROTONATION EQULIBRIA OF SHORT OLIGONUCLEOTIDES CONTAINING CYTOSIN. In Trnkova, L. X. pracovní setkání fyzikálních chemiků a elektrochemiků - sborník příspěvků. 1st ed. Brno: Mendelova univerzita v Brně, 2010, p. 84-86. ISBN 978-80-7375-396-2.

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Basic information
Original name	SPECTROSCOPIC STUDY OF PROTONATION EQULIBRIA OF SHORT OLIGONUCLEOTIDES CONTAINING CYTOSIN
Name in Czech	Protonační rovnováhy krátkých oligonukleotidů obsahujících cytosin
Authors	HOLUBOVÁ, Sylvie (203 Czech Republic, belonging to the institution), Přemysl LUBAL (203 Czech Republic, guarantor, belonging to the institution) and Libuše TRNKOVÁ (203 Czech Republic, belonging to the institution).
Edition	1. vyd. Brno, X. pracovní setkání fyzikálních chemiků a elektrochemiků - sborník příspěvků, p. 84-86, 3 pp. 2010.
Publisher	Mendelova univerzita v Brně

Other information
Original language	English
Type of outcome	Proceedings paper
Field of Study	10406 Analytical chemistry
Country of publisher	Czech Republic
Confidentiality degree	is not subject to a state or trade secret
Publication form	storage medium (CD, DVD, flash disk)
RIV identification code	RIV/00216224:14310/10:00044251
Organization unit	Faculty of Science
ISBN	978-80-7375-396-2
UT WoS	000400414900026
Keywords (in Czech)	oligonukleotidy; cytosin; rovnováhy; spektroskopie
Keywords in English	oligonucleotides; cytosine; equilibria; spectroscopy
Tags	International impact, Reviewed
Changed by	Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 2/9/2020 09:56.

Abstract
This paper deals with the spectroscopic study of protonation of short deoxyoligonucleotides (ODNs) containing cytosine. The measurements were performed at constant temperature and ionic strength. The influence of the number of cytosine in the ODNs chain on protonation was studied. The pKa values were calculated using the software OPIUM. Constants pKa determined at several temperatures provided the possibility to calculate the thermodynamic parameters such as enthalpy and entropy.

Abstract

This paper deals with the spectroscopic study of protonation of short deoxyoligonucleotides (ODNs) containing cytosine. The measurements were performed at constant temperature and ionic strength. The influence of the number of cytosine in the ODNs chain on protonation was studied. The pKa values were calculated using the software OPIUM. Constants pKa determined at several temperatures provided the possibility to calculate the thermodynamic parameters such as enthalpy and entropy.

Links
LC06035, research and development project	Name: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu.
LC06035, research and development project	Investor: Ministry of Education, Youth and Sports of the CR, Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine
MSM0021622412, plan (intention)	Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
MSM0021622412, plan (intention)	Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)