Automated Electrochemical Analyzer as a New Tool for Detection of Thiols

ADAM, Vojtěch, Ivo FABRIK, Veronika KOHOUTKOVÁ, Petr BABULA, Jaromír HUBÁLEK, Radimír VRBA, Libuše TRNKOVÁ and René KIZEK. Automated Electrochemical Analyzer as a New Tool for Detection of Thiols. INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE. 2010, 5/2010, No 4, p. 429-447. ISSN 1452-3981.

Basic information

• Original name: Automated Electrochemical Analyzer as a New Tool for Detection of Thiols
• Authors: ADAM, Vojtěch (203 Czech Republic), Ivo FABRIK (203 Czech Republic), Veronika KOHOUTKOVÁ (203 Czech Republic), Petr BABULA (203 Czech Republic), Jaromír HUBÁLEK (203 Czech Republic), Radimír VRBA (203 Czech Republic), Libuše TRNKOVÁ (203 Czech Republic, belonging to the institution) and René KIZEK (203 Czech Republic, guarantor).
• Edition: INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2010, 1452-3981.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 10405 Electrochemistry
• Country of publisher: Serbia
• Confidentiality degree: is not subject to a state or trade secret
• Impact factor: Impact factor: 2.808
• RIV identification code: RIV/00216224:14310/10:00051405
• Organization unit: Faculty of Science
• UT WoS: 000278336100001
• Keywords in English: Automated Electrochemical Detection; Drugs; Tumour Disease Markers; Proteins; Metallothioneins
• Tags: AKb, rivok

Abstract

Stationary electrochemical analysers are advantageous tools for detection of electroactive species. There advantages are low cost, sensitivity and repeatability. However, non-automated injection of samples belongs to their main disadvantages. We aim our attention to present a new electrochemical tool connected with unique autosampler enabling us to inject units of mu l, which is essential in for detection of biological samples. The analyser can be used for detection of peptides, proteins, nucleic acids, drugs. Moreover, the highest sensitivity has for thiols. The recent advances in the field of electrochemistry of mentioned biologically active compounds, mainly metallothionein, are also discussed.

Links

• MSM0021622412, plan (intention): Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)