| OČADLÍKOVÁ, Darina, Fedor KRYUKOV, Klára MOLLOVÁ, Lucie KOVÁŘOVÁ, Ivana BUREŠOVÁ, Eva MATĚJKOVÁ, Miroslav PENKA, Tomáš BÜCHLER, Roman HÁJEK a Jaroslav MICHÁLEK. Generation of myeloma-specific T cells using dendritic cells loaded with MUC1- and hTERT- drived nonapeptides or myeloma cell apoptotic bodies. Neoplasma. Bratislava, Slovenská republika: Slovak Academic Press, Ltd, roč. 57, č. 5, s. 455-464. ISSN 0028-2685. 2010. |
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@article{891888,
author = {Očadlíková, Darina and Kryukov, Fedor and Mollová, Klára and Kovářová, Lucie and Burešová, Ivana and Matějková, Eva and Penka, Miroslav and Büchler, Tomáš and Hájek, Roman and Michálek, Jaroslav},
article_location = {Bratislava, Slovenská republika},
article_number = {5},
keywords = {multiple myeloma; dendritic cells; immunotherapy; hTERT; MUC1; apoptotic bodies},
language = {eng},
issn = {0028-2685},
journal = {Neoplasma},
title = {Generation of myeloma-specific T cells using dendritic cells loaded with MUC1- and hTERT- drived nonapeptides or myeloma cell apoptotic bodies},
volume = {57},
year = {2010}
}
TY - JOUR
ID - 891888
AU - Očadlíková, Darina - Kryukov, Fedor - Mollová, Klára - Kovářová, Lucie - Burešová, Ivana - Matějková, Eva - Penka, Miroslav - Büchler, Tomáš - Hájek, Roman - Michálek, Jaroslav
PY - 2010
TI - Generation of myeloma-specific T cells using dendritic cells loaded with MUC1- and hTERT- drived nonapeptides or myeloma cell apoptotic bodies
JF - Neoplasma
VL - 57
IS - 5
SP - 455-464
EP - 455-464
PB - Slovak Academic Press, Ltd
SN - 00282685
KW - multiple myeloma
KW - dendritic cells
KW - immunotherapy
KW - hTERT
KW - MUC1
KW - apoptotic bodies
N2 - The aim of our study was to generate myeloma-specific cytotoxic T lymphocytes in vitro using dendritic cells loaded with peptide antigens or apoptotic bodies. We present a method for the priming and expansion of myeloma-specific T lymphocytes using dendritic cells loaded with different types of tumor antigens. Cytotoxic T lymphocytes and/or activated dendritic cells generated by the described methods can be applied for cellular immunotherapy against multiple myeloma and other malignancies.
ER -
OČADLÍKOVÁ, Darina, Fedor KRYUKOV, Klára MOLLOVÁ, Lucie KOVÁŘOVÁ, Ivana BUREŠOVÁ, Eva MATĚJKOVÁ, Miroslav PENKA, Tomáš BÜCHLER, Roman HÁJEK a Jaroslav MICHÁLEK. Generation of myeloma-specific T cells using dendritic cells loaded with MUC1- and hTERT- drived nonapeptides or myeloma cell apoptotic bodies. \textit{Neoplasma}. Bratislava, Slovenská republika: Slovak Academic Press, Ltd, roč.~57, č.~5, s.~455-464. ISSN~0028-2685. 2010.
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