Detailed Information on Publication Record
2010
Generation of myeloma-specific T cells using dendritic cells loaded with MUC1- and hTERT- drived nonapeptides or myeloma cell apoptotic bodies
OČADLÍKOVÁ, Darina, Fedor KRYUKOV, Klára MOLLOVÁ, Lucie KOVÁŘOVÁ, Ivana BUREŠOVÁ et. al.Basic information
Original name
Generation of myeloma-specific T cells using dendritic cells loaded with MUC1- and hTERT- drived nonapeptides or myeloma cell apoptotic bodies
Name in Czech
Tvorba myelom-specifických T lymfocytů pomocí dendritických buněk naložených nonapeptidy MUC1 a hTERT nebo myelomovými apoptotickými tělísky
Authors
OČADLÍKOVÁ, Darina (203 Czech Republic), Fedor KRYUKOV (643 Russian Federation, belonging to the institution), Klára MOLLOVÁ (203 Czech Republic, belonging to the institution), Lucie KOVÁŘOVÁ (203 Czech Republic, belonging to the institution), Ivana BUREŠOVÁ (203 Czech Republic, belonging to the institution), Eva MATĚJKOVÁ (203 Czech Republic, belonging to the institution), Miroslav PENKA (203 Czech Republic, belonging to the institution), Tomáš BÜCHLER (703 Slovakia), Roman HÁJEK (203 Czech Republic, guarantor, belonging to the institution) and Jaroslav MICHÁLEK (203 Czech Republic, belonging to the institution)
Edition
Neoplasma, Bratislava, Slovenská republika, Slovak Academic Press, Ltd, 2010, 0028-2685
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30200 3.2 Clinical medicine
Country of publisher
Slovakia
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 1.449
RIV identification code
RIV/00216224:14110/10:00040781
Organization unit
Faculty of Medicine
UT WoS
000283760800010
Keywords (in Czech)
mnohočetný myelom; imunoterapie; dendritická buňka; hTERT; MUC1; apoptotické tělísko
Keywords in English
multiple myeloma; dendritic cells; immunotherapy; hTERT; MUC1; apoptotic bodies
Změněno: 30/12/2010 07:03, Mgr. Anna Potáčová, Ph.D.
V originále
The aim of our study was to generate myeloma-specific cytotoxic T lymphocytes in vitro using dendritic cells loaded with peptide antigens or apoptotic bodies. We present a method for the priming and expansion of myeloma-specific T lymphocytes using dendritic cells loaded with different types of tumor antigens. Cytotoxic T lymphocytes and/or activated dendritic cells generated by the described methods can be applied for cellular immunotherapy against multiple myeloma and other malignancies.
In Czech
Cílem práce bylo získat myelom-specifické cytotoxické T lymfocyty pomocí dendritických buněk naložených v peptidových antigenech. Takto získané T lymfocyty mohou být využity pro buněčnou terapii mnohočetného myelomu i jiných maligních onemocnění.
Links
LC06027, research and development project |
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NR8945, research and development project |
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