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@inproceedings{893019,
author = {Holubová, Sylvie and Lubal, Přemysl and Farková, Marta and Trnková, Libuše and Hégrová, Blanka and Kristová, Petra},
address = {Pardubice},
booktitle = {Sborníi 14. česko - slovenské spektroskopické konference},
keywords = {spectroscopy; cytosine; protonation constant},
language = {eng},
location = {Pardubice},
isbn = {978-80-7395-282-2},
publisher = {Spektroskopická společnost Jana Marka Marci},
title = {Spectroscopic study of protonation of cytosine-containing oligonucleotides},
year = {2010}
}
TY - JOUR
ID - 893019
AU - Holubová, Sylvie - Lubal, Přemysl - Farková, Marta - Trnková, Libuše - Hégrová, Blanka - Kristová, Petra
PY - 2010
TI - Spectroscopic study of protonation of cytosine-containing oligonucleotides
PB - Spektroskopická společnost Jana Marka Marci
CY - Pardubice
SN - 9788073952822
KW - spectroscopy
KW - cytosine
KW - protonation constant
N2 - Cytosine is an important building block of nucleic acids taking part in the process of genetic information transfer and transfer of energy of biologically important compounds by means of coenzymes. Due to acidobasic properties of bioligands, the presence of protonated species is dependent on the protonation constants. It was also shown that oligonucleotides (ODNs) concerning cytosine can form the so called structural i motif as a consequence of probable stabilization of the secondary structure of biomacromolecules. The aim of this work was to determine the protonation constants of ODNs varying the number of bases in order to see their influence on thermodynamic stability of studied ligands.
ER -
HOLUBOVÁ, Sylvie, Přemysl LUBAL, Marta FARKOVÁ, Libuše TRNKOVÁ, Blanka HÉGROVÁ a Petra KRISTOVÁ. Spectroscopic study of protonation of cytosine-containing oligonucleotides. Online. In \textit{Sborníi 14. česko - slovenské spektroskopické konference}. Pardubice: Spektroskopická společnost Jana Marka Marci, 2010. 100 s. ISBN~978-80-7395-282-2. [citováno 2024-04-24]
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