| FIALOVÁ, Kateřina, Jana KOLÁŘOVÁ, Jiří SEKORA, Milan TANNENBERG, Marie NOVÁKOVÁ a Ivo PROVAZNÍK. Electrophysiological Effects of Voltage Sensitive Dye di-4-ANNEPS in Rabbit and Guinea Pig Isolated Heart. Analysis of Biomedical Signals and Images. Brno: Vutium Press, 2010, roč. 20, č. 1, s. 108-113. ISSN 1211-412X. |
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@article{895999,
author = {Fialová, Kateřina and Kolářová, Jana and Sekora, Jiří and Tannenberg, Milan and Nováková, Marie and Provazník, Ivo},
article_location = {Brno},
article_number = {1},
keywords = {voltage sensitive dye; isolated heart},
language = {eng},
issn = {1211-412X},
journal = {Analysis of Biomedical Signals and Images},
title = {Electrophysiological Effects of Voltage Sensitive Dye di-4-ANNEPS in Rabbit and Guinea Pig Isolated Heart},
volume = {20},
year = {2010}
}
TY - JOUR
ID - 895999
AU - Fialová, Kateřina - Kolářová, Jana - Sekora, Jiří - Tannenberg, Milan - Nováková, Marie - Provazník, Ivo
PY - 2010
TI - Electrophysiological Effects of Voltage Sensitive Dye di-4-ANNEPS in Rabbit and Guinea Pig Isolated Heart
JF - Analysis of Biomedical Signals and Images
VL - 20
IS - 1
SP - 108-113
EP - 108-113
PB - Vutium Press
SN - 1211412X
KW - voltage sensitive dye
KW - isolated heart
N2 - Voltage-sensitive dye (VSD) di-4-ANEPPS is currently used in our laboratory for recording of monophasic action potentials (MAPs) in isolated hearts. In this study, its electrophysiological effects on rabbit and guinea pig myocardium were compared during staining with VSD and washout from it. Electrograms were recorded and heart rate changes and the types and frequency of arrhythmias were evaluated. Althought certain electrophysiological changes were present in the hearts of both species, these changes are mostly reversible, especially in rabbit hearts. Thus, rabbit myocardium can be considered a reliable model for electrophysiological studies, especially when generation and propagation of the impulse is studied. It may be concluded that rabbit isolated heart is more suitable model for electrophysiological studies in the isolated heart model than guinea pig heart.
ER -
FIALOVÁ, Kateřina, Jana KOLÁŘOVÁ, Jiří SEKORA, Milan TANNENBERG, Marie NOVÁKOVÁ a Ivo PROVAZNÍK. Electrophysiological Effects of Voltage Sensitive Dye di-4-ANNEPS in Rabbit and Guinea Pig Isolated Heart. \textit{Analysis of Biomedical Signals and Images}. Brno: Vutium Press, 2010, roč.~20, č.~1, s.~108-113. ISSN~1211-412X.
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