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@inproceedings{899211,
author = {Rudolfová, Ivana and Zendulka, Jaroslav and Lexa, Matej},
address = {Heidelberg, DE},
booktitle = {ITBAM 2010 (Information Technology in Bio- and Medical Informatics), LNCS 6266},
doi = {http://dx.doi.org/10.1007/978-3-642-15020-3_9},
keywords = {Clustering; density-based clustering; clustering of protein substructures; sequence-structure relationships in proteins},
howpublished = {tištěná verze "print"},
language = {eng},
location = {Heidelberg, DE},
isbn = {978-3-642-15019-7},
pages = {94-101},
publisher = {Springer Verlag},
title = {Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments},
year = {2010}
}
TY - JOUR
ID - 899211
AU - Rudolfová, Ivana - Zendulka, Jaroslav - Lexa, Matej
PY - 2010
TI - Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments
PB - Springer Verlag
CY - Heidelberg, DE
SN - 9783642150197
KW - Clustering
KW - density-based clustering
KW - clustering of protein substructures
KW - sequence-structure relationships in proteins
N2 - In this paper, we propose a novel method for clustering of protein substructures that we developed to study the relationships between protein sequences and their corresponding structures. We show the basic properties of the new method and the results of the comparison to other commonly used methods for clustering of protein structures. The main advantage of our method is its high efficiency and scalability, which are key factors for analyzing large data sets. Finally, we outline a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.
ER -
RUDOLFOVÁ, Ivana, Jaroslav ZENDULKA and Matej LEXA. Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments. In \textit{ITBAM 2010 (Information Technology in Bio- and Medical Informatics), LNCS 6266}. Heidelberg, DE: Springer Verlag, 2010, p.~94-101. ISBN~978-3-642-15019-7. Available from: https://dx.doi.org/10.1007/978-3-642-15020-3\_{}9.
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