HYRŠL, Pavel, Pavel DOBEŠ, Zhi WANG, Thomas HAULING, Christine WILHELMSSON and Ulrich THEOPOLD. Clotting factors and eicosanoids protect against nematode infections. Online. Journal of Innate Immunity. 2011, vol. 3, No 1, p. 65-70. ISSN 1662-811X. [citováno 2024-04-24]
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Basic information
Original name Clotting factors and eicosanoids protect against nematode infections
Name in Czech Clotting factors and eicosanoids protect against nematode infections
Authors HYRŠL, Pavel (203 Czech Republic, guarantor, belonging to the institution), Pavel DOBEŠ (203 Czech Republic, belonging to the institution), Zhi WANG (156 China), Thomas HAULING (276 Germany), Christine WILHELMSSON (752 Sweden) and Ulrich THEOPOLD (752 Sweden)
Edition Journal of Innate Immunity, 2011, 1662-811X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30102 Immunology
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 4.209
RIV identification code RIV/00216224:14310/11:00049632
Organization unit Faculty of Science
UT WoS 000285568700009
Keywords (in Czech) Drosophila melanogaster; eikosanoidy; entomopatogenní hlístovky; Heterorhabditis bacteriophora; transglutamináza; koagulace; Photorhabdus luminescens
Keywords in English Drosophila melanogaster; eicosanoids; entomopathogenic nematodes; Heterorhabditis bacteriophora; transglutaminase; coagulation; Photorhabdus luminescens
Tags AKb, rivok
Tags International impact, Reviewed
Changed by Changed by: Ing. Andrea Mikešková, učo 137293. Changed: 20/4/2012 09:40.
Abstract
We show that hemolymph clotting protects Drosophila melanogaster against infections with an entomopathogenic nematode and its symbiotic bacterium. We also provide biochemical and genetic evidence for an involvement of eicosanoids in the same infection model. Taken together our results confirm the conserved nature of the immune function of clot formation.
Abstract (in Czech)
We show that hemolymph clotting protects Drosophila melanogaster against infections with an entomopathogenic nematode and its symbiotic bacterium. We also provide biochemical and genetic evidence for an involvement of eicosanoids in the same infection model. Taken together our results confirm the conserved nature of the immune function of clot formation.
Links
GP206/09/P470, research and development projectName: Vliv inhibitorů biosyntézy eikosanoidů na imunitu zavíječe voskového Galleria mellonella
Investor: Czech Science Foundation, The influence of the eicosanoid biosynthesis inhibitors to immunity of the wax moth Galleria mellonella
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