Anthracycline therapy and 24-hour blood-pressure profile in
long-term survivors of childhood cancer

J 2010

Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer

NOVÁKOVÁ, Zuzana, Jana ŠŤASTNÁ, Klára HONZÍKOVÁ, Hana HRSTKOVÁ, Nataša HONZÍKOVÁ et. al.

Basic information

Original name

Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer

Authors

NOVÁKOVÁ, Zuzana (203 Czech Republic, guarantor, belonging to the institution), Jana ŠŤASTNÁ (203 Czech Republic, belonging to the institution), Klára HONZÍKOVÁ (203 Czech Republic, belonging to the institution), Hana HRSTKOVÁ (203 Czech Republic, belonging to the institution), Nataša HONZÍKOVÁ (203 Czech Republic, belonging to the institution), Eva ZÁVODNÁ (203 Czech Republic, belonging to the institution), Bohumil FIŠER (203 Czech Republic, belonging to the institution) and Petr HONZÍK (203 Czech Republic)

Edition

Physiological Research, Praha, Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, 0862-8408

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.646

RIV identification code

RIV/00216224:14110/10:00051469

Organization unit

Faculty of Medicine

UT WoS

000279049100014

Keywords in English

anthracyclines; blood pressure; cardiotoxicity; childhood cancer; chronobiology

Abstract

V originále

In our previous studies, a decreased blood pressure was reported in children treated by anthracycline (AC). The aim of this study was to assess the long-term effects of AC anticancer therapy in 45 subjects aged 13-22 years by repeated 24-hour Holter monitoring of blood pressure.It is concluded that blood pressure in 19-22 years old AC patients is lower during night hours, the age-dependent increase of blood pressure seen in healthy controls between 13 and 22 years of age does not occur in patients. This finding is consistent with the long-lasting impairment of the sympathetic nervous system caused by anthracyclines.

Links

MSM0021622402, plan (intention)

Name: Časná diagnostika a léčba kardiovaskulárních chorob

Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases

Citovat

NOVÁKOVÁ, Zuzana, Jana ŠŤASTNÁ, Klára HONZÍKOVÁ, Hana HRSTKOVÁ, Nataša HONZÍKOVÁ, Eva ZÁVODNÁ, Bohumil FIŠER and Petr HONZÍK. Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer. Physiological Research. Praha: Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, vol. 59, Suppl 1, p. "S97"-S102", 6 pp. ISSN 0862-8408.

@article{900493,
   author = {Nováková, Zuzana and Šťastná, Jana and Honzíková, Klára and Hrstková, Hana and Honzíková, Nataša and Závodná, Eva and Fišer, Bohumil and Honzík, Petr},
   article_location = {Praha},
   article_number = {Suppl 1},
   keywords = {anthracyclines; blood pressure; cardiotoxicity; childhood cancer; chronobiology},
   language = {eng},
   issn = {0862-8408},
   journal = {Physiological Research},
   title = {Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer},
   volume = {59},
   year = {2010}
}

TY  - JOUR
ID  - 900493
AU  - Nováková, Zuzana - Šťastná, Jana - Honzíková, Klára - Hrstková, Hana - Honzíková, Nataša - Závodná, Eva - Fišer, Bohumil - Honzík, Petr
PY  - 2010
TI  - Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer
JF  - Physiological Research
VL  - 59
IS  - Suppl 1
SP  - "S97"-S102"
EP  - "S97"-S102"
PB  - Institute of Physiology,Academy of Sciences of the Czech Republic
SN  - 08628408
KW  - anthracyclines
KW  - blood pressure
KW  - cardiotoxicity
KW  - childhood cancer
KW  - chronobiology
N2  - In our previous studies, a decreased blood pressure was reported in children treated by anthracycline (AC). The aim of this study was to assess the long-term effects of AC anticancer therapy in 45 subjects aged 13-22 years by repeated 24-hour Holter monitoring of blood pressure.It is concluded that blood pressure in 19-22 years old AC patients is lower during night hours, the age-dependent increase of blood pressure seen in healthy controls between 13 and 22 years of age does not occur in patients. This finding is consistent with the long-lasting impairment of the sympathetic nervous system caused by anthracyclines.
ER  -

NOVÁKOVÁ, Zuzana, Jana ŠŤASTNÁ, Klára HONZÍKOVÁ, Hana HRSTKOVÁ, Nataša HONZÍKOVÁ, Eva ZÁVODNÁ, Bohumil FIŠER and Petr HONZÍK. Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer. \textit{Physiological Research}. Praha: Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, vol.~59, Suppl 1, p.~''S97''-S102'', 6 pp. ISSN~0862-8408.

Detailed Information on Publication Record