NOVÁKOVÁ, Zuzana, Jana ŠŤASTNÁ, Klára HONZÍKOVÁ, Hana HRSTKOVÁ, Nataša HONZÍKOVÁ, Eva ZÁVODNÁ, Bohumil FIŠER and Petr HONZÍK. Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer. Physiological Research. Praha: Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, vol. 59, Suppl 1, p. "S97"-S102", 6 pp. ISSN 0862-8408.
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Basic information
Original name Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer
Authors NOVÁKOVÁ, Zuzana (203 Czech Republic, guarantor, belonging to the institution), Jana ŠŤASTNÁ (203 Czech Republic, belonging to the institution), Klára HONZÍKOVÁ (203 Czech Republic, belonging to the institution), Hana HRSTKOVÁ (203 Czech Republic, belonging to the institution), Nataša HONZÍKOVÁ (203 Czech Republic, belonging to the institution), Eva ZÁVODNÁ (203 Czech Republic, belonging to the institution), Bohumil FIŠER (203 Czech Republic, belonging to the institution) and Petr HONZÍK (203 Czech Republic).
Edition Physiological Research, Praha, Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, 0862-8408.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30105 Physiology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.646
RIV identification code RIV/00216224:14110/10:00051469
Organization unit Faculty of Medicine
UT WoS 000279049100014
Keywords in English anthracyclines; blood pressure; cardiotoxicity; childhood cancer; chronobiology
Tags International impact
Changed by Changed by: Mgr. Michal Petr, učo 65024. Changed: 10/4/2012 08:56.
Abstract
In our previous studies, a decreased blood pressure was reported in children treated by anthracycline (AC). The aim of this study was to assess the long-term effects of AC anticancer therapy in 45 subjects aged 13-22 years by repeated 24-hour Holter monitoring of blood pressure.It is concluded that blood pressure in 19-22 years old AC patients is lower during night hours, the age-dependent increase of blood pressure seen in healthy controls between 13 and 22 years of age does not occur in patients. This finding is consistent with the long-lasting impairment of the sympathetic nervous system caused by anthracyclines.
Links
MSM0021622402, plan (intention)Name: Časná diagnostika a léčba kardiovaskulárních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases
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