WITTE, Florian, Ondřej BERNATÍK, Katharina KIRCHNER, Jan MAŠEK, Annika MAHL, Pavel KREJČÍ, Stefan MUNDLOS, Alexandra SCHAMBONY, Vítězslav BRYJA and Sigmar STRICKER. Negative regulation of Wnt signaling mediated by CK1- phosphorylated Dishevelled via Ror2. FASEB JOURNAL. 2010, vol. 24, No 7, p. 2417-2426. ISSN 0892-6638. Available from: https://dx.doi.org/10.1096/fj.09-150615. |
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@article{901334, author = {Witte, Florian and Bernatík, Ondřej and Kirchner, Katharina and Mašek, Jan and Mahl, Annika and Krejčí, Pavel and Mundlos, Stefan and Schambony, Alexandra and Bryja, Vítězslav and Stricker, Sigmar}, article_number = {7}, doi = {http://dx.doi.org/10.1096/fj.09-150615}, keywords = {Wnt/beta-catenin signaling; casein kinase; Ror2}, language = {eng}, issn = {0892-6638}, journal = {FASEB JOURNAL}, title = {Negative regulation of Wnt signaling mediated by CK1- phosphorylated Dishevelled via Ror2}, volume = {24}, year = {2010} }
TY - JOUR ID - 901334 AU - Witte, Florian - Bernatík, Ondřej - Kirchner, Katharina - Mašek, Jan - Mahl, Annika - Krejčí, Pavel - Mundlos, Stefan - Schambony, Alexandra - Bryja, Vítězslav - Stricker, Sigmar PY - 2010 TI - Negative regulation of Wnt signaling mediated by CK1- phosphorylated Dishevelled via Ror2 JF - FASEB JOURNAL VL - 24 IS - 7 SP - 2417-2426 EP - 2417-2426 SN - 08926638 KW - Wnt/beta-catenin signaling KW - casein kinase KW - Ror2 N2 - Dishevelled (Dvl) is a multifunctional effector of different Wnt cascades. We provide evidence that Dvl phosphorylated by casein kinase 1 epsilon can bind atypical receptor kinase Ror2. We show that CK1-phosphorylated Dvl induced by both canonical and non-canonical Wnt ligands triggers negative feedback regulation in a Ror2-dependent manner. ER -
WITTE, Florian, Ondřej BERNATÍK, Katharina KIRCHNER, Jan MAŠEK, Annika MAHL, Pavel KREJČÍ, Stefan MUNDLOS, Alexandra SCHAMBONY, Vítězslav BRYJA and Sigmar STRICKER. Negative regulation of Wnt signaling mediated by CK1- phosphorylated Dishevelled via Ror2. \textit{FASEB JOURNAL}. 2010, vol.~24, No~7, p.~2417-2426. ISSN~0892-6638. Available from: https://dx.doi.org/10.1096/fj.09-150615.
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