Early Warning Biosensors for Detection of Chemical Warfare Agents.

BIDMANOVÁ, Šárka, Michal POHANKA, J. CABAL, Zbyněk PROKOP and Jiří DAMBORSKÝ. Early Warning Biosensors for Detection of Chemical Warfare Agents. CHEMICKE LISTY. Česká republika, 2010, vol. 104, No 104, p. 302-308. ISSN 0009-2770.

Basic information

• Original name: Early Warning Biosensors for Detection of Chemical Warfare Agents.
• Name in Czech: Biosenzory včasného varování pro detekci bojových chemických látek
• Name (in English): Early Warning Biosensors for Detection of Chemical Warfare Agents.
• Authors: BIDMANOVÁ, Šárka (203 Czech Republic, belonging to the institution), Michal POHANKA (203 Czech Republic), J. CABAL (203 Czech Republic), Zbyněk PROKOP (203 Czech Republic, belonging to the institution) and Jiří DAMBORSKÝ (203 Czech Republic, guarantor, belonging to the institution).
• Edition: CHEMICKE LISTY, Česká republika, 2010, 0009-2770.

Other information

• Original language: Czech
• Type of outcome: Article in a journal
• Field of Study: 10600 1.6 Biological sciences
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 0.620
• RIV identification code: RIV/00216224:14310/10:00040597
• Organization unit: Faculty of Science
• UT WoS: 000278253900002
• Keywords (in Czech): nervově paralytické látky; zpuchýřující otravné látky; biosenzor; acetylcholinesterasa;butyrylcholinesterasa; halogenalkandehalogenasa; fosfotriesterasa
• Keywords in English: Chemical warfare agents;toxic compounds;biosensors
• Tags: Reviewed

Abstract

Bojové otravné látky jsou chemické sloučeniny vykazující negativní účinky na živé organismy. Z hlediska ustáleného členění dělíme ve vojenství používané otravné látky na nervově paralytické, zpuchýřující, všeobecně toxické (otravné), dusivé a psychoaktivní1.

Abstract (in English)

Chemical warfare agents are toxic compounds showing negative effects on living organisms. This review focuses on detection of nerve and blister agents, which are two most important classes of chemical warfare agents. Main attention is paid to the construction and use of biosensors. Acetylcholinesterase, butyrylcholinesterase and phosphotriesterase are presented as convenient biorecognition components of biosensors for detection of nerve agents, while dehalogenases are useful for detection of mustard agents.

Links

• GA203/08/0114, research and development project: Name: Specifické iontové efekty pro proteiny v roztocích a podobné biologicky relevantní systémy.

Investor: Czech Science Foundation, Specific ion effects for proteins in solutions and related biologically relevant systems

• IAA401630901, research and development project: Name: Evoluce substrátové specifity u enzymů aktivních s xenobiotickými látkami

Investor: Academy of Sciences of the Czech Republic, Evolution of substrate specificity in enzymes acting on xenobiotic compounds

• LC06010, research and development project: Name: Centrum biokatalýzy a biotransformací

Investor: Ministry of Education, Youth and Sports of the CR, Center of Biocatalysis and Biotransformation

• MSM0021622412, plan (intention): Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)

• MSM0021622413, plan (intention): Name: Proteiny v metabolismu a při interakci organismů s prostředím

Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment